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Expressiona and Diagnostic Potential of miRNAs in NSCLC

The Expression Profiling of Serum miRNAs (106b-5p, 601, and 760) in Non-small Cell Lung Cancer Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05815407
Enrollment
100
Registered
2023-04-18
Start date
2018-09-01
Completion date
2022-09-30
Last updated
2023-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non Small Cell Lung Cancer

Brief summary

Its to explore the expression pattern, diagnostic and prognostic potentials of miRs (106b-5p, 601 and 760) in serum of NSCLC patients

Detailed description

A retrospective observational study on NSCLC patients, to determine the serum expression levels if some miRNAs in NSCLC patients and to find if having proper diagnostic and prognostic values in early disease detection, and/or staging.

Interventions

OTHERNo intervention

No intervention

Sponsors

National Cancer Institute, Cairo University, Egypt
CollaboratorUNKNOWN
Al-Azhar University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* First time and recently diagnosed NSCLC patient

Exclusion criteria

* Recurrent NSCLC * Start of chemotherapy, radiotherapy or surgical intervention * Previous treatment * Cancer history

Design outcomes

Primary

MeasureTime frameDescription
Determination of the expressionBy the end of the study (September 2022)Expression profiling of the selected miRNAs

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026