Gingival Recession, Soft Tissue Infections
Conditions
Brief summary
Free gingival grafting surgeries require palatal grafts harvesting from the patient own palates . The donor sites pain , infection and retarded healing by secondary intension are the complication .
Detailed description
After the preparation and characterization of the solid dispersion of hydroxylated methoxy flavones, free gingival grafting surgeries require palatal grafts harvesting from the patient own palates . The donor sites pain , infection and retarded healing by secondary intension are the complications ; the aim of the study is to assess the analgesic , anti inflammatory effects of hydroxylated methoxy flavones.
Interventions
DRUGhydroxylate flavones solid dispersion application
this drug has the antibacterial and anti inflammatory actions could help the palatal donor sites to promote the wound healing
OTHERPlacebo
Dough inert material without any therapeutic action
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* insufficient zone of keratinized gingiva recession of the gingiva non smokers free from systemic disorders
Exclusion criteria
* smokers insufficient palatal donor sits un realistic expectations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| post operative pain (VAS scale) | first day postoperative to 30 days (days) | VAS scale from 0 no pain to 10 excruciating pain (healing) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of analgesic and anti inflammatory pills consumed | first day postoperative to 30 days (days) | Minimizing the pain and inflammation during healing process post operative swelling |
Countries
Egypt
Contacts
Primary ContactAhmed Mortada, professor
Outcome results
None listed