Epidemiology of Occult Hepatitis C Virus Infection in Patients Born Before 1969 in the Hospital Setting: a Spontaneous Opportunistic Screening Initiative.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05813691

Acronym

ERADIcATE

Enrollment

4000

Registered

2023-04-14

Start date

2023-04-10

Completion date

2025-04-10

Last updated

2023-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis, Hepatitis C, Hepatitis C, Chronic

Keywords

hepatitis C virus

Brief summary

The goal of this monocentric prospective observational study is to evaluate the prevalence of unknown hepatitis C virus chronic infection in general population born before january 1st 1968 in Italy. The main questions it aims to answer are: what is the prevalence of hepatits C virus infection in general population born before January 1st, 1968? What rare the characteristics of these patients compared to the general population? What is the prevalence of patients tested HCV positive who are referred to the Hepatology Outpatient Clinic for further evaluation? What is the prevalence of patients with HCV infection detected during the study and treated with direct antiviral agents during follow up? Participants will be tested with a point of care screening test (Meridian, Bioscience) able to detect anti-HCV antibodies to detect the presence of antibodies against HCV.

Interventions

DIAGNOSTIC_TESTMeridan Bioscience Point of Care test against HCV antibodies

Point of care evaluation of antibodies against HCV obtaining a drop of capillary blood via puncture of the fingertip. If antibodies were detected, HCV RNA assay will be performed.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

54 Years to 120 Years

Inclusion criteria

* Patients born before January 1st 1968 who lived in Italy referred to any departments of the Policlinico A. Gemelli

Exclusion criteria

* Patients born after january 1st 1968 * Known infection of hepatitis C virus * Previous treatment against hepatitis C virus

Design outcomes

Primary

Measure	Time frame	Description
prevalence of antibodies against hepatitis C virus in cohort population	24 months	Evaluation of prevalence of antibodies against HCV in patients referred to any department of Policlinico Gemelli born before January 1st 1968

Secondary

Measure	Time frame
Characteristics of population	24 months
Prevalence of patients with a confirmed chronic HCV infection who are referred to Hepatology Outpatient clinic	24 months
Prevalence of patients with a confirmed chronic HCV infection who are treated with direct antiviral agents	24 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026