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Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration

Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration in Horizontal Ridge Augmentation in Aesthetic Zone

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05813340
Acronym
VIP-CT
Enrollment
24
Registered
2023-04-14
Start date
2023-01-01
Completion date
2023-12-01
Last updated
2023-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Horizontal Ridge Deficiency

Keywords

VIPCTF, GBR, Horizontal ridge augmentation

Brief summary

this study compares 2 techniques in guided bone regeneration for horizontal ridge augmentation in aesthetic zone

Detailed description

Guided bone regeneration is a technique for ridge augmentation using membranes The membrane of GBR is an essential component of treatment as it has some important characteristics manageability, space-making ability, and adequate mechanical, physical properties, and biocompatibility Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects and achieve better wound healing and bone regeneration. on the other hand, a Vascularized inter-positional periosteal connective tissue flap is a flap that has been used as a substitute for the collagen membrane with promising results. Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability. So Evaluation of effect of vascularized interpositional periosteal connective tissue flap on horizontal ridge augmentation grafting of the anterior maxilla in comaprison with the collagen membranes

Interventions

PROCEDUREVascularized inter-positional periosteal connective tissue flap

It is a vascularized pedicled flap derived from the hard palate that can be used as a barrier to prevent in growth of soft tissue in guided bone regeneration and to increase soft tissue quantity

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients with a horizontal defect in anterior and premolar areas of the maxilla (aesthetic zone).

Exclusion criteria

* poor oral hygiene * radiation therapy of head and neck cancer * intraoral soft and hard tissue lesions * Heavy smoking * Bone pathology

Design outcomes

Primary

MeasureTime frameDescription
Amount of bone width gain (horizontal augmentation)6 monthsbone width gain is measured in millimeters by Cone beam computed tomography

Secondary

MeasureTime frameDescription
Percentage of bone formation in the bone biopsy6 monthsArea percentage of newly formed bone is measured through histomorphometric analysis

Countries

Egypt

Contacts

Primary ContactEsraa Ismail, Masters
esera.hady@dentistry.cu.edu.eg01155400246
Backup ContactRofaida Atef, PhD
01289980034

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026