Hand Function, Stroke
Conditions
Keywords
Hand Function, Rehabilitation, stroke rehabilitation, Motor control, Hand Rehabilitation, Neurorehabilitation
Brief summary
10 participants with upper-limb impairment will be recruited from community sources. They will be invited to participate in a 15-day trial involving the IRegained device. The study will involve 2 assessment visits to McMaster, before and after the treatment, and 15 treatment visits. The data from the pilot study will be analyzed both quantitatively and qualitatively, as outcomes and explicit feedback from participants will be used to further optimize the device for future studies.
Detailed description
This pilot study will investigate the potential changes in the brain area controlling hand movement following 15 days of exercises to improve hand function in participants with upper limb impairments resulting from stroke. A device developed by Dr. Vineet Johnson (IRegained Inc.) will be used to administer standardized exercises to improve hand function. To assess brain changes, transcranial magnetic stimulation pulses will be delivered to the motor cortex. The motor evoked potential (MEP), a muscle response evoked from the TMS, will be measured using electrodes on the hand. This study will test the feasibility of conducting motor therapy using this device while assessing potential changes in motor cortex function. Findings from this study will contribute to developing treatment trials aimed at improving impaired limb function in stroke patients and quality of life in these individuals
Interventions
Participants will undergo three weeks of 1-hour hand therapy with the MyHand System. The MyHand System provides a highly unique and targeted approach to hand function rehabilitation with the help of the aforementioned protocols delivered with gamified training techniques. The gamified format of the protocols allows for better patient engagement, thus allowing for more effective and efficient therapy.
Sponsors
Baycrest
McMaster University
IRegained Inc.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
-Sustained a single stroke \>6months prior to start of study
Exclusion criteria
* Severe spasticity or contractures (2 or less in the CMSA) * any other musculoskeletal or neuromuscular disorders that compromise sensation * Prospective participants who are incapable of providing consent to participate in the research study will also be excluded (determined by an MMSE score of 23 or less).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Chedoke Arm and Hand Activity Inventory 9 (CAHAI-9)- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | a 9-item assessment, will be performed by a trained clinician to estimate a participants functional ability during the initial assessment. The CAHAI-9 requires a participant to perform 9 bimanual ADLs, each of which will be scored on a 7 point scale. |
| ABILHAND- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | a subjective functional assessment tool will be used. The tool is a 23-item survey, and participants are provided with a list of various everyday functional tasks and are scored based on patient response. For example, participant will be asked whether it is 'easy', 'difficult' or 'impossible' for each of the 23 tasks. |
| Box and Block (BBT)- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | The BBT requires participants to move cubical wooden blocks over a partition from one box to another. Grip and pinch dynamometry will be used to assess a participant's hand strength. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Finger Goniometry- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | Estimate range of motion (ROM) of the various finger joints. |
| Grip Dynamometry- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | Measures participants grip strength |
| Pinch Dynamometry- Change is being assessed | Baseline- before beginning the treatment and Post treatment- after the conclusion of 15 treatment sessions, within 5 days | Measures participants pinch strength |
Countries
Canada
Contacts
Primary ContactRavjot Rehsi, MSc
Backup ContactMikayla Marshall
Outcome results
None listed