RL Versus Glucose Saline in Cancer Patient Undergoing Major Surgeries and Its Impact on Electrolytes, GLC & pH

Randomized Study of Intraoperative Glucose Saline Versus Ringer Lactatein Cancer Pediatric Patients Doing Major Surgeries and Impact on Electrolytes ,Glucose and pH

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05810662

Enrollment

Registered

2023-04-12

Start date

2022-09-04

Completion date

2023-12-31

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid and Electrolyte Imbalance

Brief summary

To compare two electrolytes maintenance in perioperative period in children undergoing major surgeries on perioperative change in pH,lactate,sodium and glucose level

Detailed description

Patients were randomized into 2 groups ringer lactate versus 5%dextrose in 0.9% saline,using a computer generated random list in blocks of 4 after recruitment the enrolling investigators opened sealed opaque envelopes that concealed group allocation participants ,trial investigators,attending anesthetist providing general anesthesia for the cases and the outcomes were blinded to group allocation

Interventions

OTHERLactated ringer and dextrose 5%

Fluid use perioperative

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

1 Years to 10 Years

Healthy volunteers

Inclusion criteria

* 1to 10 years Children undergoing major surgeries ie considered major if any invasive procedure in which extensive resection will be preformed e.g body cavity is opened,organs are removed and normal anatomy is altered abd duration not less than 2 hours or more than 5 hours.

Exclusion criteria

* patient guardian refusal \_ Children with documented endocrine distrubances(DM,inborn error of metabolism,hyperthyroidism) * age less than one year * preexisting renal disease,hepatic disease and patien suffering from heart failure. * preexisting electrolyte imbalance (normal sodium level 135-145)

Design outcomes

Primary

Measure	Time frame	Description
PH and lactate level	In the introperative period	Three ABG will be collected from the patient. The first at start before any intervention,the second after start of replacement and the third at the end of the operation.

Secondary

Measure	Time frame	Description
Sodium and glucose level	The intraoperative period	Three ABGs will be collected.The first at the start of the operation before any surgical intervention,the second after the start of fluid replacement and the last sample at the end of the operation.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026