Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

Comparison of Erector Spina and Quadratus Lumborum in Open Nephrectomy

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05810571

Enrollment

Registered

2023-04-12

Start date

2024-10-24

Completion date

2027-01-03

Last updated

2024-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Cell Carcinoma

Keywords

erector spina plane block, quadratus lumborum block, patient controlled analgesia, nephrectomy, analgesia

Brief summary

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Detailed description

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Interventions

PROCEDUREpreoperative remifentanil consumption

continuous remifentanil infusion will applied for peroperative analgesia

PROCEDUREpostopeartive controlled anlagesia with morphine

postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

DIAGNOSTIC

Masking

DOUBLE (Subject, Outcomes Assessor)

Masking description

participant will not know which block applied, and the outcome assessor of the postoperative analgesia will not know

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* ASA 1-3 * open nephrectomy elective patients * BMI\<35

Exclusion criteria

* ASA 4-5-6 * Laparoscopic nephrectomy * infection at the block side * coagulation disorder * BMI\>35

Design outcomes

Primary

Measure	Time frame	Description
postoperative morphine consumption	24 hour postoperatively	amount of postoperative morphine use of the patient's

Secondary

Measure	Time frame	Description
peroperative remifentanil consumptions	4 hour preoperatively	amount of remifentanil use of the patient's
numeric rating scale	24 hour postoperatively	numeric rating scores of the patient's postoepartively

Countries

Turkey (Türkiye)

Contacts

Primary Contactzehra ipek Arslan AYDIN, Professor

zehraipek48@gmail.com00905325011339

Backup ContactZehra ipek Arslan, Professor