OCT and OCT-A Deep Learning in Diabetic Patients Wiht Artificial Pancreas Device

Deep Learning in Vascular and Structural Retinal Changes in Diabetic Patients Undergoing Artificial Pancreas Device

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05809843

Enrollment

Registered

2023-04-12

Start date

2023-01-30

Completion date

2023-03-23

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes Mellitus With Artificial Pancreas Device

Brief summary

This study evaluates the ability of deep learning to improve the knowledge about structural and vascular retinal changes in diabetic patients undergoing artificial pancreas device, using optical coherence tomography angiography.

Detailed description

hybrid artificial pancreas systems (CSII) are able to adjust the type 1 diabetic patient's glycemic levels with insulin doses appropriate to the patient's blood glucose. The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed and quantitative analysis of retinal and choriocapillary vascular features. The study evaluates the changes in optical coherence tomography angiography features in diabetic patients undergoing artificial pancreas device, elaborating these data with artificial intelligence.

Interventions

DEVICEhybrid artificial pancreas systems (CSII)

artificial device that adjust the patient's glycemic levels with insulin doses appropriate to the patient's blood glucose

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* • age older than 18 years * diagnosis of type 1 diabetes * treatment with artificial pancreas device * absence of previous ocular surgery and congenital eye diseases. * absence of errors of refraction * absence of lens opacities * absence of low-quality OCT and OCTA images

Exclusion criteria

* age younger than 18 years * previous ocular surgery and congenital eye diseases * errors of refraction * lens opacities * low-quality OCT and OCTA images

Design outcomes

Primary

Measure	Time frame	Description
The measurements of retinal and choriocapillary vessel density in type 1 diabetic patients undergoing artificial pancreas device	up to 3months	The parameters analyzed by optical coherence tomography angiography were: retinal and choriocapillary vessel density matched with clinical parameters resulted from the artificial pancreas device

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026