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Periodontal Disease Prediction System

Periodontal Disease Prediction System and a Patient-Specific Gingival Recession Simulator

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05809570
Enrollment
1057
Registered
2023-04-12
Start date
2020-06-01
Completion date
2022-06-01
Last updated
2023-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases

Keywords

gingival recession, Oral hygiene motivation, Computer-aided design

Brief summary

The purpose of this study was to develop a periodontal disease prediction software and a patient-based gingival recession simulator for clinical practice aiming at improving oral hygiene motivation of patients with periodontal problems.

Detailed description

Periodontal Disease Prediction (PDP) software has three components: a) Data Loading Window (DLW) b) Three-Dimensional Mouth Model (3DM) and c) Periodontal Attachment Loss Indicator (PLI). Demographic and clinical examinations of 1057 volunteers were recorded to DLW. An unsupervised machine learning K means clustering analysis was used to categorize the data obtained from the study population and identified the periodontal risk groups. An intraoral scanner was utilized to capture direct optical intraoral data of a patient and transferred to the 3DM. The intraoral model went under two algorithm steps for obtaining a recessed model. First, gingival curves separating gingiva and tooth were extracted using a Dijkstra's algorithm. Limit curves determining boundaries of recessed regions in the intraoral model were then obtained using gingival curves. The gingival recession was then mimicked by losing gingiva and disappearing tooth roots at proper locations in the intraoral model and Additionally, the final four different 3 dimensional recessed model (maxilla, mandibula, anterior teeth and posterior teeth) belonging to the same patient were scored based on the similarity to the real gingival recession by 25 periodontology specialist via online survey.

Interventions

DIAGNOSTIC_TESTClinical examination

A total of 1057 individuals who applied to Bolu Abant İzzet Baysal University, Faculty of Dentistry, Department of Periodontology and agreed to participate in the study were clinically and radiologically examined. An intraoral scanner was utilized to capture direct optical intraoral data of a patient.

Sponsors

Abant Izzet Baysal University
CollaboratorOTHER
Istanbul Technical University
CollaboratorOTHER
The Scientific and Technological Research Council of Turkey
CollaboratorOTHER
Bezmialem Vakif University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age greater than 18 years, * Periodontal status ranging from no clinical periodontal disease (\<10% with bleeding on probing) to periodontitis (stage I to IV) * Patients having at least one teeth in each quadrant were included.

Exclusion criteria

* Patients undergoing orthodontic treatment and using anti-inflammatory drugs were excluded.

Design outcomes

Primary

MeasureTime frameDescription
Number of sites Clinical Attachment Loss≥5 mmBaselineCategorized as: None, \<4, 4-8, \>8

Secondary

MeasureTime frameDescription
Patient cooperation and awarenessBaselineCategorized as: None, some, high
History of dental treatmentBaselineCategorized as: None, treated in the last 1 year
Tooth brushing HabitsBaselineCategorized as: None/ 1 time in day/ ≥2 times in day
Presence of diabetesBaselineCategorized as: Absence, diabetes with HbA1c\<7, diabetes with HbA1c≥7
Interproximal cleaningBaselineCategorized as: None/ 1 time in day/ ≥2 times in day
Alveolar bone loss/ageBaselineCategorized as: None/ \<0.25 /0.25-1/ \>1
Number of sites Probing Pocket Depth ≥5 mmBaselineCategorized as: None/ \<4 / 4-8/ \>8
Number of sites Bleeding on Probing (%)BaselineCategorized as: \<10%/ 10-25%/ \>25%
Smoking statusBaselineCategorized as: None, \< 10 per day, ≥10 per day
Gingival phenotypeBaselineCategorized as: Thin/thick
Presence of furcation involvementBaselineCategorized as: None/ horizontal involvement/ vertical involvement/ combined
Vertical alveolar bone lossBaselineCategorized as: Presence/absence
Presence of endodontic tooth problemBaselineCategorized as: Presence/absence
Number of tooth lossBaselineCategorized as: None/ \<4/ 4-8/ \>8
Traumatic occlusionBaselineCategorized as: Presence/absence
Restorations including gingival marginBaselineCategorized as: Presence/absence
Tooth mobilityBaselineCategorized as: None/ Miller I/ Miller II/ Miller III

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026