NICE - Nutritional Impact on Immunological Maturation During Childhood in Relation to the Environment

Conditions

Chronic Diseases in Children

Brief summary

Role of the exposome on allergy, caries, and neurophysiological development in childhood.

Detailed description

Role of the exposome and epigenetics on allergy, caries, and neurophysiological development in childhood as studied in a birth cohort of 650 trioses. The exposome includes repeated measures of nutrition, micronutritients, microbiota, toxic agents and the clinical outcomes, diagnoses of allergy, caries and neurophysiological functions/dysfunctions.

Mia Stråvik, Anna Sandin, Bill Hesselmar, Agnes E. Wold, Malin Barman et al. (6 authors)

Nutrition Journal2026-06-17

10.1186/s12937-026-01344-4

Longitudinal Plasma Ferritin in the First Year of Life in Relation to Maternal Status, Birth Characteristics, and Breastfeeding

Mia Stråvik, Inger‐Cecilia Mayer Labba, Malin Barman, Linnea Svärd, Nathalie Scheers et al. (8 authors)

Nutrients2026-05-22

10.3390/nu18111657

LC-MS-Based Metabolomics for Dietary Biomarker Discovery in a Cohort of Pregnant and Lactating Women and Their Infants

Mia Stråvik, Olle Hartvigsson, Stefania Noerman, Anna Sandin, Agnes E. Wold et al. (7 authors)

2023-11-20

10.3390/proceedings2023091061

Interventions

OTHERNo intervention

No intervention

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 6 Years

Healthy volunteers

Yes

Inclusion criteria

* Born at Sunderby hospital, Region Norrbotten, during time period 2015-2018

Exclusion criteria

* Parents not able to speak or write Swedish

Design outcomes

Primary

Measure	Time frame	Description
Number of participants with excema	Outcome at one year	Excema
Number of participants with food allergy	Outcome at one year	Food allergy
Number of participants with frhino-conjuctivitis	Outcome at one year	Rhino-conjunctivitis
Number of participants with asthma	Outcome at one year	Asthma
Number of participants with rhino-conjunctivitis	Outcome at four years	Rhino-conjuctivitis
Numbers of caries lesions (DeMFS = decayed, enamel included, missed, filled, tooth surfaces, in each child	Outcome at four years	Cariesfree individuals have a DeMFS = 0 and increasing scores means increasing degree of caries. Maximum DeMFS = 148, minumum DeMFS = 0.
Child cognition as measured by Wechsler Preschool and Primary Scale of Intelligence	Outcome at four years	Cognitive development will be tested face-to-face with Wechsler Preschool and Primary Scale of Intelligence. Increasing scores means increasing intelligence.

Countries

Sweden

Outcome results

None listed