Transplant;Failure,Kidney
Conditions
Keywords
transplant, mindfulness, mindful breathing
Brief summary
To study the effectiveness of single session 20-minute mindful breathing in symptom control in kidney transplant recipients.
Detailed description
Patients undergoing kidney transplant follow ups in our center are screened based on recruitment criteria. Patients who fulfilled the incusion criteria are recruited. Intervention involves a 20-minute mindful breathing session with uniform script performed by trained personal, while control arm involves standard care without intervention.
Interventions
OTHER20-minute mindful breathing session
A 20-minute mindful breathing session guided by a trained medical doctor. The session consisted of four 5-minute breathing exercises done consecutively. Participants were instructed to close their eyes and bring their attention to their breathing, and re-direct their attention back to their breathing once they were distracted.
Sponsors
University of Malaya
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Intervention model description
This is a parallel-group, non-blinded, randomized controlled trial conducted at the University of Malaya Medical Centre, Malaysia. Patients were recruited from the transplant clinic, the renal day care unit and the nephrology ward. Participants were randomly assigned to either intervention or control based on computer generated random number with 1:1 allocation ratio. Allocations were concealed with sealed envelopes.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult renal transplant patients aged 18 years and older * At least one symptom scoring ≥ 4/10 based on the Edmonton Symptom Assessment Scale (ESAS)
Exclusion criteria
* Dialysis-dependent * Medically unstable * Having serious pre-existing mental health issues
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Participant-rated Edmonton Symptom Assessment Scale (ESAS) scores at 0 minute and 20 minute | 20 minutes | ESAS is a validated scale to assess 10 symptoms commonly experienced by patients, which are: pain, fatigue, nausea, depression, anxiety, drowsiness, shortness of breath, anorexia, other symptoms, and feelings of well-being. The severity of each symptom was rated on a numerical scale of 0 to 10 (0 = no symptom; 10 = worst possible symptom). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Within-group comparison of Edmonton Symptom Assessment Scale (ESAS) scores at 0 minute and 20 minute | 20 minutes | Statistical anaylsis done using paired t-tests. |
| Between-group comparison of changes in Edmonton Symptom Assessment Scale (ESAS) scores | 20 minutes | Statistical anaylsis done using independent sample t-tests |
Countries
Malaysia
Outcome results
None listed