Endometrial Cancer
Conditions
Brief summary
In this context, the aim of this study is to investigate the role of MRF in endometrial cancer. Several applications are possible. Firstly, T1-, T2- and DWI-mappings can be associated to molecular risk group classification, in order to stratify patients' risk without recurring to surgery. MRF parameters can be also correlated to prognosis, both in terms of disease-free survival (DFS) and overall survival (OS).
Interventions
None listed
Sponsors
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with biopsy-proven endometrial cancer; * Women aged \> 18 years old; * Signed Informed consent.
Exclusion criteria
* Previous history of neoplasm; * Concurrent malignancies at other sites.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Association between T1-, T2- and diffusion-mappings and risk group classification | 3 months |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of T1-,T2- and diffusion-mappings deriving from MRF in myometrial invasion detection | 3 months |
| Correlation between T1-, T2- and diffusion mappings and DFS and OS | 3 years |
| Diagnostic accuracy of T1-,T2- and diffusion-mappings and pathological nodal involvement | 3 months |
| Evaluation of Radiomic and Radiogenomic models to predict recurrence in early stage EC and to predict DFS and OS | 3 years |
Countries
Italy
Contacts
Primary ContactBenedetta B Gui, MD
Backup ContactBenedetta B Gui, MD
Outcome results
None listed