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Evaluation of Anterior Cruciate Ligament Tears Using Diffusion Tractography

Evaluation of Anterior Cruciate Ligament Tears Using Diffusion Tractography

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05806034
Acronym
TRACTOLCA
Enrollment
30
Registered
2023-04-10
Start date
2023-02-08
Completion date
2026-01-21
Last updated
2026-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACL Injury, MRI, Tractography

Keywords

ACL Injury, MRI, tractography

Brief summary

Knees injuries commonly affect the ACL. French current methodology is based on MRI focused on the knee with morphological sequences (T1, DP fat sat) allowing the study of ACL as follows: No lesion / Partial tear / Complete tear. The treatment (kinesitherapy, surgery, no intervention) is defined taking into account several factors such as age, knee laxity, physical activity and outcome of the radiology analysis (partial or complete tear). However, if the classification is straightforward in case of complete tear, it is not possible to establish a quantitative impact on the ACL in case of partial tear. As a consequence, the investigators will analyze the anisotropy coefficient with diffusion tractography. Any patient who undergo a posttraumatic knee MRI at the CHU Amiens Picardie will have an appointment at the 3T "Signa" MRI that has the knee-centric diffusion tractography sequence.

Interventions

OTHERtractography MRI sequence protocol

tractography MRI sequence protocol does not require injection of contrast agent.

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 years old, * Patient referred for non-enhanced knee MRI for traumatism. * Affiliation to a social security program,

Exclusion criteria

* Person under guardianship or curators, * Any contraindications to MRI

Design outcomes

Primary

MeasureTime frameDescription
Anisotropy score after tractography MRI sequenceone dayAnisotropy coefficient value is between 0 (isotropic medium) to 1 (fibrillar medium) . Anisotropy coefficient =0 is for total ACL rupture Anisotropy coefficient between 0 end 0.8 is for partial ACL rupture
Correlation between anisotropy coefficient and ACL lesion stateone yearAnisotropy coefficient value is between 0 (isotropic medium) to 1 (fibrillar medium) . Anisotropy coefficient =0 is for total ACL rupture ACL lesion state are No lesion, Partial tear or Complete tear

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 12, 2026