Pneumonia, Viral, Covid19, Respiratory Failure
Conditions
Keywords
COVID19 pneumonia, Diaphragm ultrasound
Brief summary
We hypothesized that diaphragm thickness is concerned in acute respiratory failure of COVID19 patients and its ultrasound measure at the begining of hospitalisation is a good predictor of poor outcome. A prospective observational non intervention study is designed.
Detailed description
To answer our hypothesis we will perform diaphragm ultrasound in the first 24hr hospitalized COVID19 patients. In the ultrasound exploration we will assess diaphragm movility and thickness. We will also assess other clinical, biochemistry and radiological variables. The main outcome we want to analyze is the destination on discharge: home, respiratory intermediate critical unit or exitus.
Interventions
DIAGNOSTIC_TESTDiaphragmatic echography
Diaphragmatic echography
Sponsors
Sociedad Aragonesa de Patología del Aparato Respiratorio
Javier Lázaro
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* COVID19 Pneumonia Acute respiratory failure (PaO2 \<60mmHg)
Exclusion criteria
* Invasive or non invasive ventilation within first 24h Neuromuscular disease Diaphragmatic paralysis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Early diaphragm ultrasound as a predictor factor for invasive and non invasive ventilation and death | From date of inclusion until discharge date (lenght of hospitalization) | This is the main outcome of our study given that it has a important clinical implications. If we confirm our hypothesis diaphragm ultrasound could prove to be a useful prognosis tool for COVID19 patients. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diaphragm thickness rate as a predictor factor for invasive and non invasive ventilation and death | From date of inclusion until discharge date (lenght of hospitalization) | Diaphragm strenght is directly related to thickness. The impact of COVID19 infection on this specific measure can predict patient evolution. |
| Diaphragm movility rate as a predictor factor for invasive and non invasive ventilation and death | From date of inclusion until discharge date (lenght of hospitalization) | Diaphragm fatigability is directly related to movility. The impact of COVID19 infection on this specific measure can predict patient evolution. |
Countries
Spain
Outcome results
None listed