HIV Infections
Conditions
Keywords
Men Who Have Sex with Men, Latino men, HIV PrEP, Siblings
Brief summary
This is a randomized controlled trial with an attention placebo control group. The goal of this study is to decrease HIV incidence in Latino men who have sex with men by engaging their siblings in PrEP-use promotion. In the intervention arm, siblings will be trained to engage their gay brother in PrEP conversations. In the control arm, siblings will be trained to engage their gay brother in conversations about vaccines to prevent COVID, Hepatitis A/B, or MPOX.
Interventions
BEHAVIORALEntre Herman@s
The intervention unfolds as follows: (Week 1) the research team, Latino MSM, \& sibling will all engage in a PrEP Conversation followed by an individual Sibling Training for siblings to learn communication strategies for promoting health behaviors; (Week 2) we will send siblings reminders and a link to motivational interviewing techniques; (Week 3) we will conduct brief Follow-ups with siblings to determine if their brother changed his behavior; (Week 4) we will send a reminder to Latino MSM that they will have a follow-up the following week; (Week 5) we will conduct 30-day Follow-up with Latino MSM to determine if there was uptake of the new behavior change; (Week 7) same as week 5 above; (Week 10) send siblings information on motivational interviewing; (Week 12) final follow-up for both Latino MSM and siblings.
BEHAVIORALVaccines for Health
The intervention unfolds as follows: (Week 1) the research team, Latino MSM, \& sibling will all engage in a Health Conversation about vaccines for COVID, Hep A/B, or MPOX, followed by an individual Sibling Training for siblings to learn communication strategies for promoting health behaviors; (Week 2) we will send siblings reminders and a link to motivational interviewing techniques; (Week 3) we will conduct brief Follow-ups with siblings to determine if their brother changed his behavior; (Week 4) we will send a reminder to Latino MSM that they will have a follow-up the following week; (Week 5) we will conduct 30-day Follow-up with Latino MSM to determine if there was uptake of the new behavior change; (Week 7) same as week 5 above; (Week 10) send siblings information on motivational interviewing; (Week 12) final follow-up for both Latino MSM and siblings.
Sponsors
Charles Drew University of Medicine and Science
St. Johns Community Health
National Institute on Minority Health and Health Disparities (NIMHD)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 39 Years
Healthy volunteers
Yes
Inclusion criteria
Latino Men Who Have Sex with Men 1. self-identify as Latino 2. identify as male 3. be \<40 years old 4. report HIV-negative status 5. be willing to talk about MSM healthcare issues with a sibling 6. either (a) have never used PrEP or (b) stopped using PrEP at least 90 days ago 7. missing most recent COVID vaccine 8. missing Hepatitis (A or B) vaccines 9. missing Mpox vaccine 10. meet CDC's PrEP eligibility criteria (be HIV-negative; any male sex partner in the past six months; not in a monogamous partnership with a recently tested, HIV-negative man; and at least one of the following: any anal sex without condoms in past 6 months, any sexually-transmitted infection (STI) diagnosed or reported in past 6 months, or is in an ongoing sexual relationship with an HIV-positive male partner).
Exclusion criteria
Latino Men Who Have Sex with Men 1. are unable to provide consent or 2. they do not meet any of the criteria above Inclusion Criteria: Siblings 1. at least 18 years old 2. report a close relationship his/her LMSM brother \<40 years old 3. be willing to talk about MSM healthcare issues with his/her LMSM brother
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants that start using PrEP | 90 days | This measures how many participants in the experiment group started taking PrEP (baseline = 0 participants). Tool: Pictures. Participants will submit a picture of their pill bottle to report PrEP use. |
| Number of participants that get vaccinated | 90 days | This measures whether participants in the control group decided to get vaccinated for COVID, Hep A/B, or MPOX. Tool: Pictures. Participants will submit a picture of their proof-of-vaccination card to report vaccination status. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants who increase their willingness to use PrEP | 90 days | This measures whether participants progress along the stages of change (e.g., pre-contemplation, contemplation, action) in their willingness to try PrEP if it were available to them. Tool: Stages of Change questionnaire administered at baseline and 90 days. |
| Number of participants who increase their willingness to get vaccinated | 90 days | This measures whether participants progress along the stages of change (e.g., pre-contemplation, contemplation, action) in their willingness to get vaccinated against COVID, Hep A/B, or MPOX if it were available to them. Tool: Stages of Change questionnaire administered at baseline and 90 days. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORHomero del Pino, PhD, MS
Charles Drew University of Medicine and Science
Outcome results
None listed