Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Clinical Study of Abandonment of Intravenous Volume Expansion After Preoperative Use of α-blockers in Patients With Adrenal Pheochromocytoma

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05803330

Enrollment

Registered

2023-04-07

Start date

2014-02-20

Completion date

2022-10-20

Last updated

2023-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adrenal Pheochromocytoma, Hemodynamic

Brief summary

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

Detailed description

All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.

Interventions

DRUGAbandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma

Abandonment of intravenous volume expansion with alpha-blockers during preoperative preparation in patients with pheochromocytoma

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets

Exclusion criteria

Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma

Design outcomes

Primary

Measure	Time frame	Description
intraoperative mean arterial pressure	During surgery	an intraoperative mean arterial pressure \<60 mmHg is considered to be hemodynamically unstable

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026