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Asymmetry of the Center of Pressure During Gait After Amputation of Lower Limbs

Asymmetry of the Center of Pressure During Gait After Amputation of Lower Limbs

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05803317
Acronym
ASCOPALL
Enrollment
130
Registered
2023-04-07
Start date
2023-08-01
Completion date
2024-03-15
Last updated
2025-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)

Brief summary

Retrospective, non-randomized, observational, single-center longitudinal study at the University Rehabilitation Hospital of Grau du Roi CHU of Nîmes, France. From January 2012 to Janvier 2023 patients hospitalized for lower limb amputation, were extracted from the computer database of the motion analysis laboratory (2 baropodometric platforms, Zebris, Germany). All patients with lower limb amputations, unilateral or bilateral, walking with or without technical aids, were included regardless of the level (trans-femoral or trans-tibial). Only patients hospitalized in the locomotor rehabilitation department were included in the study. Patients who were not autonomous for walking and required a third person (human assistance) were not included. Finally, deceased patients were also excluded from the study population. Prior to data collection, all participants received a note of non-objection. The study was reported on the Health Data Hub, and data collection and analysis were performed according to the MR004 reference methodologies. Walking amputee patients hospitalized in the locomotor rehabilitation department benefited from a systematic gait assessment before discharge from hospital after rehabilitation and validation of the prosthesis. During the gait analysis, on baropodometric platforms, the software provides a number of parameters: spatiotemporal, pressure distribution, vertical component of the ground reaction force and trajectory of the center of pressure. All patients were recorded over a distance of ten meters including the two meters of acceleration and deceleration according to the validity of the TM-10 for a duration of two minutes. The parameters from the CoP trajectory are calculated from the coordinates calculated in the platform reference frame. A processing of these data will be specially developed within the service. Three key parameters of the COP have been retained: Lateral symmetry (LS; the left/right offset of the intersection point, where the zero position is equivalent to perfect symmetry), lateral variability (LV; the standard deviation of the intersection point in the lateral direction, where zero equals constant steps in terms of width between the legs), and anteroposterior variability (APV; the standard deviation of the intersection point in the anteroposterior direction, where zero equals constant strides while walking on the treadmill). These parameters, which allow for the assessment of continuous COP trajectories with multiple strides, reflect the overall movements of individuals throughout the gait cycle.

Interventions

OTHERusual care : Evaluation of walking on a baropodometric platform

Pure observationnal study

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* unilateral or bilateral lower limb amputees, walking with or without technical aids, hospitalized in the Locomotor Rehabilitation Department * Adult patient (≥18 years) and less than 90 years of age.

Exclusion criteria

* Patients not autonomous for walking requiring a third person (human assistance) were not included. Finally, deceased patients were also excluded from the study population. * Patients who objected to the use of their data.

Design outcomes

Primary

MeasureTime frameDescription
Lateral symmetryBaselineMeasurement of the lateral symmetry of the center of pressure (LS; the left/right offset of the point of intersection, where the zero position is equivalent to perfect symmetry)
Lateral variabilitybaselineMeasurement of the Lateral variability of the center of pressure (LV; the standard deviation of the point of intersection in the lateral direction, where zero is equivalent to constant steps in terms of width between the legs)
Anteroposterior variabilitybaselineMeasurement of the Anteroposterior variability of the center of pressure (APV; the standard deviation of the point of intersection in the anteroposterior direction, where zero is equivalent to constant strides while walking on the treadmill)

Secondary

MeasureTime frameDescription
Walking speedbaselineMeasurement of the median speed according to the level of amputation and the use or not of a technical aid (in m/sec)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026