Cognitive Impairment, Consciousness Disorder
Conditions
Brief summary
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness. Identify potential markers with prognostic value, in order to identify personalized and specific intensive rehabilitation paths based on the outcome indexes obtained.
Interventions
DIAGNOSTIC_TESTNeurowave Group
Neurosensory stimulation will consist in the administration of pairs of stimuli consisting of emotionally significant images and sounds in the personal life history (two rare stimuli) alternating with neutral images and sounds devoid of emotional significance (two distracting stimuli
Sponsors
IRCCS Centro Neurolesi Bonino Pulejo
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Glasgow Coma Scale (GCS) \> 8; Level of Cognitive Scale (LCF) = 1-3; Signature of the consent from the family member and/or guardian.
Exclusion criteria
* Failure to sign the consent of the family member and/or legal guardian; Patients with cranial anatomical alterations that do not allow the correct assembly of the electrodes, caps, etc.; Patients with absence of neurophysiological responses in visual evoked potentials (VEP) and with absence of peripheral waves (I-II wave) to acoustic potentials (PEA).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Event-related evoked potentials(ERPs) | 24 months | Event-related evoked potentials(ERPs) are variations of the electric potential deriving from a visual, somesthetic or auditory stimulus. |
Countries
Italy
Outcome results
None listed