Parkinson Disease, Physical Disability
Conditions
Brief summary
Comparison of two rehabilitation protocols in patients with Parkinson's disease and, therefore, identification of innovative rehabilitation protocols of proven and validated efficacy, through which it is possible to achieve: * Improved joint function and gait pattern * Reduction of the risk of falling or reduction of energy expenditure during physiological gait Evaluation of the increase in maximal effort tolerance · Improved cognitive performances Evaluation of the impact on the quality of life of the patient and family members Identification of morpho-functional markers predictive of clinical and rehabilitative out-come through neuroimaging study.
Detailed description
rehabilitation protocols in patients with Parkinson's disease and, therefore, identification of innovative rehabilitation protocols of proven and validated efficacy, through which it is possible to achieve: Improved joint function and gait pattern Reduction of the risk of falling or reduction of energy expenditure during physiological gait Evaluation of the increase in maximal effort tolerance · Improved cognitive performances Evaluation of the impact on the quality of life of the patient and family members Identification of morpho-functional markers predictive of clinical and rehabilitative out-come through neuroimaging study.
Interventions
DEVICEIRMA
For patients in an advanced state of illness, advanced neuromotor rehabilitation treatment included 1) robot therapies, 2) specific water courses (e.g. walking pools, hydrokinesiotherapy pools, etc.), 3) advanced cognitive treatments (e.g. virtual reality courses); 4) augmentative immersive therapy in a virtual environment; 5) courses also dedicated to social reintegration and inclusive activities (theatre-therapy, art-therapy, dance-therapy, agro-therapy, etc.).
Sponsors
IRCCS Centro Neurolesi Bonino Pulejo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Hoehn & Yahr between 2.0 and 3.0; * No need for a walking aid; * Mini-Mental State Examination (MMSE) score \>24; * Effective dopaminergic pharmacological control; * Absence of other relevant neurological comorbidities; * Absence of postural deformities (and/or Pisa syndrome); * Absence of severe cardiological pathologies (exertional angina, severe decompensation). * Ability to travel to the rehabilitation treatment site independently or with support
Exclusion criteria
* presence of Deep Brain Stimulation (DBS); * presence of severe heart and/or lung disease; * presence of therapeutic regimen in the definition phase; * impaired joint and/or motor function to follow a proposed rehabilitation treatment programme * contraindications to performing MRI scans * undergoing rehabilitation therapy in the 3 months preceding enrolment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Berg Balance Scale (BBS) | 8 weeks | The Berg Balance Scale is a scale for assessing balance and the risk of falling |
Countries
Italy
Outcome results
None listed