Adverse Reaction to Food, Food Allergy, Food Intolerance
Conditions
Brief summary
Since the prevalence of adverse reactions to foodstuffs (ARFS) has been steadily increasing and has become an alarming health concern, the general objective of this study is to analyze the prevalence of ARFS in Spanish adults of different physical condition.
Detailed description
Individuals with associated diseases and symptomatology to ARFS will be selected and will be clinically and physically measured.
Interventions
OTHERAllergen-specific substitute diet
Substitution of IgG4 allergen-specific reactive foodstuffs for equivalent foodstuffs with similar nutritional value.
Sponsors
Universidad Politecnica de Madrid
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Diseases and symptomatology associated to ARF.
Exclusion criteria
* Participation in other study. * Pregnancy. * Antibiotic treatment. * Active Helicobacter pylori infection. * Antidepressant, sleeping pill, or anxiolytic treatment. * Job or lifestyle that potentially interferes with your regular sleep schedule. * Active Cancer treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Immunoglobulin G4 and E response in subjects with subjective symptoms of adverse reactions to food. | 4-month intervention | Immunoglobulin G4 and E reported in kilounits per liter through HELIA® Helmed Line Immunoassay. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body composition in sedentary and physically active population. | 4-month intervention | Weight and Height will be combined to report BMI in kg/m\^2 through Tanita equipment model MC-780MA. |
| Physical condition in sedentary and physically active population. | 4-month intervention | Maximum rate of oxygen reported in VO₂max using GE Olmeda TuffSat®. |
| General health in subjects with subjective symptoms of adverse reactions to food. | 4-month intervention | Health measured using number of cells reported in x10\^6/mm\^3 through spectrometry-flow cytometry Smty®. |
Countries
Spain
Contacts
Primary ContactLisset S Pantoja Arevalo, MSc
Backup ContactMarcela Gonzalez Gross, Prof Dr
Outcome results
None listed