Diabetes Mellitus
Conditions
Brief summary
The purpose of this study is to evaluate the natural history of coronary atherosclerosis development and progression over time by CCTA and to identify risk factors attributable to the development of coronary atherosclerosis in a Korean DM population.
Detailed description
Patients with diabetes mellitus, who underwent initial CCTA (coronary computed tomographic angiography) at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012, will be evaluated for inclusion in the study. All DREAM-CCTA study patients will undergo follow-up CCTA based on order from their primary physician. CCTA and demographic data, medical history, cardiovascular risk factors, and laboratory data was collected in case report forms at the time of the initial CCTA and at the time of follow-up CCTA.
Interventions
None listed
Sponsors
Asan Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 19 years or older * Asymptomatic patients with type 2 DM who had undergone initial CCTA evaluation at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012 * Willing and able to provide informed written consent
Exclusion criteria
* Blood test results that the Creatinine level exceeds 1.5 mg/dL * A person with a history of anaphylaxis or allergic shock associated with a contrast medium * Pregnant women * Unable to undergo follow-up CCTA * Uninterpretable CCTA
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change in coronary atherosclerosis detected by initial and follow-up CCTA | about 10 years after first CCTA | the natural history of coronary atherosclerotic plaque development and progression over time by CCTA |
Countries
South Korea
Contacts
CONTACTJi Sue HONG, RN
CONTACTSeung-Whan Lee, MD
Outcome results
None listed