Non-surgical Treatment of Peri-implant Mucositis: FMUD vs FMUD and Air-Flow Master Piezon®

Treatment of Peri-implant Mucositis: Adjunctive Benefit of Glycine Powder Air Polishing Device to Professional Mechanical Biofilm Removal. A Randomized Parallel Arm Clinical Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05801315

Enrollment

Registered

2023-04-06

Start date

2020-03-01

Completion date

2023-03-20

Last updated

2023-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-implant Mucositis

Keywords

Peri-implant Mucosits, air polishing device, non-surgical treatment

Brief summary

The aim of the present study is to evaluate the adjunctive effect of glycine-powder air-polishing (GPAP) to full-mouth ultrasonic debridement (Fm-UD) in the treatment of peri-implant mucositis, and to determine the predictive role of implant and patient-level variables for disease resolution. Both treatments are described in the literature, but few studies are available on their comparison.

Detailed description

52 patients (132 implants) with peri-implant mucositis were included in this randomized parallel arm clinical study. Following baseline variables assessment, participants received Fm-UD. Implants allocated to the test group (n=64) were additionally treated with GPAP. Clinical outcomes were evaluated at 3 and 12 months following intervention. Complete and partial disease resolution were defined as absence of BoP (DR1) or \<2 BoP+ sites (DR2), respectively.

Interventions

DEVICEGlycine powder air polishing

Peri-implant mucositis sites treated with a glycine powder air polishing device (Air-Flow Master Piezon®).

DEVICEFull mouth ultrasonic debridement

Peri-implant mucositis sites are treated with thin ultrasonic tips.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* age between 18 and 70 years old; * presence of one implant loaded at least one year before; * bleeding on probing and/or suppuration of the peri-implant mucosa; * pain and/or tenderness of the peri-implant mucosa; * good general health conditions.

Exclusion criteria

* radiographic bone loss ≥ 2mm; * intake of anticoagulants, antiplatelet, antibiotic or cortisone drugs; * inability to perform oral hygiene maneuvers.

Design outcomes

Primary

Measure	Time frame	Description
Bleeding on probing	12 months	After probing dental and implant sites a dichotomic value (0/1) is assigned for each site. 0: not bleeding site; 1: bleeding site.

Secondary

Measure	Time frame	Description
Probing pocket depth change	12 months	Change in probing pocket depth measured in millimeter through a periodontal probe.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026