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JUMP Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients

Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05800535
Acronym
JUMP
Enrollment
100
Registered
2023-04-05
Start date
2025-02-10
Completion date
2029-02-10
Last updated
2025-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Sarcopenia

Keywords

Post cancer, Chemobrain, Sarcopenia, Medical evaluation

Brief summary

Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease. Thus, the reconquest of a life after cancer becomes possible but raises many challenges for the patient, his entourage, the medical profession and our society. One of the major challenges is the detection and management of treatment side effects for all patients. In addition to the standard organic assessment (glycaemia, creatinine, liver test, blood count), we are mainly interested in muscle deconditioning and cognitive impairment, which are particularly disturbed in these populations. After the evaluation day, patients are referred to the most appropriate structures (Adapted physical activity, sports for health, and rehabilitation at Henry Gabriel Hospital). JUMP research is part of axis 2 of the 2021-2030 cancer plan: Limiting sequelae and improving quality of life, through sheets 1 (research) / 6 (access and quality) / 7 (prevention). This leads to the concrete implementation on the territory of adapted care channels in the city: medical structure, physiotherapy, Adapted Physical Activity (APA) structures, associative structures; which makes it possible to develop and strengthen the city-hospital link. Finally, it allows the patient to take ownership and get involved in the project, allowing in the future to make them truly active in they care and to advise and motivate their peers. This study is non-interventional, it uses research on data that is already collected as part of conventional care, during the JUMP evaluation day. This study allows the investigators to constitute a cohort of patients to study different parameters related to the disease or to the treatments received. Our main objective in this study is to describe the muscular and neurocognitive impairment of post-cancer patients evaluated as part of the JUMP program.

Interventions

DRUGStudy of the adverse effects of long-term oncological treatments

Cognitive and muscular evaluation of patients who have received oncological treatments, away from the latest treatments to assess their impacts

BEHAVIORALStudy of the long-term side effects of oncological treatments on the anxiety-depressive and cognitive state of patients

Cognitive and anxiety-depressive evaluation of patients who have received oncological treatments, away from the latest treatments to assess their impacts

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 74 Years
Healthy volunteers
No

Inclusion criteria

* Age : 18 to 74 years * localization of the primitive: breast, lung, melanoma, testicle, bladder, kidney, ovary, colon and pancreas, hemopathy * patient who benefited from the post-cancer assessment day-

Exclusion criteria

* Under 18years * Over 74 years * Patient who did not received any chemical treatment * Patient who do not wish to participate

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of patients with physical and neurocognitive impairmentat least 1 year later after chemical treatmentsNumber of patients whose medical assessments show altered physical, cognitive or anxiety/dpression activity compared to the measurement in the general population

Countries

France

Contacts

Primary ContactCyrille CONFAVREUX, MD
Cyrille.confavreux@chu-lyon.fr+334 78 86 12 31

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026