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Analysis of Heart Rate Variability After a Physical Exercise Session

Analysis of Heart Rate Variability After One Session of Aerobic or Resistance Physical Exercise in Controlled Hypertensive Individuals: Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05798975
Enrollment
36
Registered
2023-04-05
Start date
2022-04-01
Completion date
2024-11-30
Last updated
2025-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Brief summary

Systemic arterial hypertension (SAH) is a multifactorial clinical condition, characterized by sustained elevation of blood pressure levels, contributing to 50% of deaths from cardiovascular disease. The Autonomic Nervous System (ANS) plays a fundamental role in the regulation of Blood Pressure (BP) and is closely associated with Heart Rate (HR). HR changes are called Heart Rate Variability (HRV). In individuals with SAH, HRV indices are reduced compared to normotensive individuals, showing changes in autonomic modulation, thus increasing the risk for cardiovascular events. The objective of this study will be to analyze the Heart Rate Variability in individuals with controlled SAH after a session of aerobic (EA) or resistance (RE) physical exercise.

Detailed description

Controlled hypertensive individuals aged between 30 and 59 years will be selected, for convenience, who use the services of the Instituto de Cardiologia do Rio Grande do Sul. Volunteers will be randomly assigned to an EA session (40 minutes on cycle ergometer, 60% of heart rate reserve) or RE (2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM) or control group without exercise. HRV data will be collected by ECG (Wincardio USB - Version 11.1.0.0, MICROMED Biotecnologia Ltda, Brasília - DF - Brazil) during 10 minutes before the exercise session, 10 minutes after the exercise session, 1h and 2h post-session . It is expected to estimate results that may demonstrate clarifications about the impact of a physical exercise session on HRV in controlled hypertensive individuals.

Interventions

OTHERAerobic Exercise. 1 session of acute exercise

40 minutes on cycle ergometer, 60% of heart rate reserve

OTHERResistance Exercise. 1 session of acute exercise

2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM. 40 minutes

OTHERno exercise

Rest

Sponsors

Instituto de Cardiologia do Rio Grande do Sul
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Caregiver)

Intervention model description

AE= Aerobic Exercise RE= Resistance Exercise CT= Control (no exercise)

Eligibility

Sex/Gender
ALL
Age
30 Years to 59 Years
Healthy volunteers
No

Inclusion criteria

* Controlled Systemic Alterial Hypertension

Exclusion criteria

* Diabetes mellitus; * heart failure; * coronary artery disease; * chronic renal failure; * body mass index (BMI) ≥ 35 kg/m2; * smokers; * individuals with injuries to the upper and lower limbs that make the exercise protocol impossible; * not using antihypertensive medication and using beta-blocker and/or alpha-blocker medication.

Design outcomes

Primary

MeasureTime frameDescription
Heart Rate Variability.4 hoursAnalysis of heart rate variability with Wincardio Digital ECG.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026