Erector Spinae Block Versus PENG Block for Hip Replacement

Erector Spinae Block Versus PENG Block for Postoperative Analgesia After Total Hip Replacement

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05796804

Acronym

PENGESP

Enrollment

Registered

2023-04-04

Start date

2023-04-13

Completion date

2024-05-23

Last updated

2024-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative

Brief summary

THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Erector Spinae Plane Block (ESPB) and PENG (pericapsular nerve group block) are alternative approaches to the hip sensitive nerve branches that resulted to be very promising for hip surgeries. However, no studies investigated the analgesic superiority of either PENG or ESPB. In our study the investigators compare PENG (with a lateral femoral cutaneous nerve block) and ESPB in terms of pain relief expressed as morphine consumption in the first 24 hours after primary THR.

Interventions

PROCEDUREERECTOR SPINAE PLANE BLOCK

ULTRASOUND GUIDED - ROPIVACAINE 30 ml 0.5%

PROCEDUREPeng block + lateral femoral cutaneous nerve block

ULTRASOUND GUIDED - ROPIVACAINE 20 ml 0.5% + 10 ml 0.5%

PROCEDUREspinal anesthesia

bupivacaine 0.5% 2.2 ml

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* primary total hip replacement * informed consent

Exclusion criteria

* allergies to study drugs * spinal anesthesia contraindicated * kidney failure * epilepsy, psychiatric disease, neurologic deficits * revision surgery * neuropathies in the lumbar area * no informed consent * pregnancy * alcohol/opioid abuse * emergency surgery/intensive care

Design outcomes

Primary

Measure	Time frame	Description
morphine consumption	24 hours	milligrams of morphine by patient controlled analgesia intravenously

Secondary

Measure	Time frame	Description
postoperative pain	48 hours	numeric rating scale - NRS 11 point scale from 0 = no pain to 10 = worst imaginable pain
neuropathic pain	48 hours	DN4 questionnaire - 4 items questionnaire to investigate the occurrence of neuropathic component
postoperative complications	48 hours	nausea, vomiting, vertigo, blurred vision, syncope, bleeding, falls
chronic postoperative pain	3 months	numeric rating scale 11 point scale from 0 = no pain to 10 = worst imaginable pain

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026