Delayed Dinner, Exercise Plus Delayed Dinner, Normal Dinner
Conditions
Keywords
late dinner, postprandial Glycaemia
Brief summary
This study aims to investigate whether exercise can alleviate the impact of delayed dinner on metabolic health next morning in sedentary healthy adults
Interventions
Participants will consume breakfast at 0830-0855 am, lunch at 1230-1255 pm, followed by dinner at 1800-1825 pm. Snacks will be consumed at 2130-2140 pm.
Participants will consume breakfast at 08:30-08:55 am, lunch at 12:30-12:55 pm, followed by snacks at 18:00-18:10 pm. Dinner will be consumed at 21:30-21:55 pm.
Participants will consume breakfast at 08:30-08:55 am, lunch at 12:30-12:55 pm, followed by snacks at 18:00-18:10 pm. Participants will exercise for 45 min at moderate-intensity 45 min prior to the delayed dinner at 21:30-21:55 pm.
Sponsors
Study design
Eligibility
Inclusion criteria
* Physical inactive males * Weight stable for more than 3 months (no change in weight +/- 3%) * Non-smoker * Able to walk comfortably on a treadmill * Dinner consumers with normal sleep pattern (cycles)
Exclusion criteria
* Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia * Taking medications that may influence lipid or carbohydrate metabolism or immune system function * Unable to take part in exercise for any reason (e.g., injury or disability) or a positive response to any questions on the Physical Activity Readiness questionnaire (PAR-Q)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Metabolic health (Oral glucose tolerance test, OGTT) | 120 minutes | Fasting and postprandial blood glucose responses on next morning between trials |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale (VSA) | 120 minutes | Changes in VAS from 0-100 mm (e.g., appetite & mood, etc.) on next morning between trials |
| Substate oxidation | 120 minutes | Lipid and carbohydrate oxidation during OGTT between trials |
| Blood pressure | 120 minutes | Changes in blood pressure (systolic and diastolic blood pressure) on next morning between trials |
| Inflammation | Baseline | Fasting inflammatory biomarkers (IL-6, TNF-a, CRP) on next morning between trials |
| HRV | Baseline | Heart rate variability on next morning between trial |
| Gut hormones | 120 minutes | Changes in blood gut hormones responses on next morning (e.g., GLP-1, PYY and GIP) between trials |
| Appetite (lunch intake) | 30 minutes | Ab libitum energy intake on next morning by the end of trial |
Countries
Taiwan