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Spot Reduction in Male Adults

The Assessment of Spot Reduction in Adults Males Following Endurance Training

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05794854
Enrollment
16
Registered
2023-04-03
Start date
2005-08-31
Completion date
2006-05-31
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

endurance exercise, subcutaneous tissue utilization

Brief summary

Spot reduction, referring to local body fat reduction, pertains to subcutaneous adipose tissue utilization from specific body parts during exercise. Its existence has been keenly debated, although generally accepted not to occur during exercise. However, it is based on not only equivocal data - commonly the training protocol typically applied is based on strength rather than endurance training. The investigators sought to test this assumption by utilizing endurance based exercise controlling for energy expenditure and using dual x-ray absorptiometric measures to assess body composition before and after training.

Interventions

OTHERAbdominal aerobic endurance exercise

Subjects combined treadmill running at 70% HRmax (27 minutes) with 4x4minutes (30-40% maximal strength, 1RM) of torso rotation and abdominal crunches (57 minutes), 4 days per wk for 10 weeks

OTHERControl training intervention

Subjects performed treadmill running (45 minutes) at 70% HRmax 4 days per week for 10 weeks

Sponsors

Norwegian University of Science and Technology
CollaboratorOTHER
Molde University College
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)

Masking description

Assessor of dual x-ray absorptiometry results was blinded to group allocation

Eligibility

Sex/Gender
MALE
Age
30 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* males * ≥ 30 years old * classified as overweight (Body mass index ≥ 25 kg ∙ m-2) * not participating in regular physical training

Exclusion criteria

* \< 30 years old * Body mass index \< 25 kg ∙ m-2 * participating in regular physical training

Design outcomes

Primary

MeasureTime frameDescription
Trunk fat mass changeChange from pre (baseline) to post test (after 10 weeks)Fat mass located in trunk (g) measured by dual-energy x-ray absorptiometry

Secondary

MeasureTime frameDescription
Lower extremity fat mass changeChange from pre (baseline) to post test (after 10 weeks)Fat mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry
Hip circumference (cm) changeChange from pre (baseline) to post test (after 10 weeks)
Upper extremity fat mass changeChange from pre (baseline) to post test (after 10 weeks)Fat mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry
Total fat mass changeChange from pre (baseline) to post test (after 10 weeks)Total fat mass (g) measured by dual-energy x-ray absorptiometry
Body weight changeChange from pre (baseline) to post test (after 10 weeks)
Body mass index changeChange from pre (baseline) to post test (after 10 weeks)
Waist circumference (cm) changeChange from pre (baseline) to post test (after 10 weeks)

Other

MeasureTime frameDescription
Upper extremity lean mass changeChange from pre (baseline) to post test (after 10 weeks)Lean mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry
Total lean mass changeChange from pre (baseline) to post test (after 10 weeks)Total lean mass (g) measured by dual-energy x-ray absorptiometry
Maximal oxygen uptake changeChange from pre (baseline) to post test (after 10 weeks)Maximal oxygen uptake by cardiopulmonary indirect calorimetry
Maximal muscle strength changeChange from pre (baseline) to post test (after 10 weeks)One-repetition maximum (kg) in torso rotation and abdominal crunch
Lower extremity lean mass changeChange from pre (baseline) to post test (after 10 weeks)Lean mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry
Trunk lean mass changeChange from pre (baseline) to post test (after 10 weeks)Lean mass located in trunk (g) measured by dual-energy x-ray absorptiometry

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026