Sedation Problems
Conditions
Keywords
Sedation, capnography, Respiratory rate, colonoscopy
Brief summary
Although appropriate sedation is recommended during colonoscopy, patients are at risk for adverse events e.g hypoventilation and hypoxemia due to inadvertent oversedation. The aim of this study was to evaluate the benefit of additional quantitative capnography monitoring ( respiratory rate )in management of patient undergoing colonoscopy under sedation in preventing or reducing the incidence of adverse events and also determine when to start the procedure and when to give and not to give increments of sedative drugs during the procedure.
Interventions
PROCEDUREStandard capnography
Patients undergoing colonoscopy under sedation were randomly assigned to receive standard capnography monitoring or modified capnography monitoring which can be achieved by tucking capnography probe under the face mask.74 patients were enrolled. Patient characteristics were well balanced between the two groups 37 patients in each group.
PROCEDUREModified capnography
If Respiratory rate below 14 b/m: more sedation isn't not advised and the patient may develop airway obstruction and needs airway intervention ( like jaw thrust or oral airway) If respiratory rate more than 20 b/m it means this patient is prone to awake or to move and this patient in need for incremental dose of sedative drug ( e.g 20 to 30 mg propofol) Also roughly speaking respiratory rate from 16 to 18 b/m is the target
Sponsors
Al Jedaani Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* ASA 1 and 2 adult patients * Age from 20 to 50 years old * elective colonoscopy
Exclusion criteria
* American Society of Anesthesiologists (ASA) above Class II * History of psychiatric or neurological disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypoxemia | 1 hours | Detected by pulse oximeter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient movements during the procedure | 1 hour | Measured by questionnaire to the gastroenterologist (scale from 1 to 5) |
| Effort exerted by the anesthesiologist ( the provider) | 1 hour | Measured by questionnaire ( scale from 1 to 5 ) |
| Patient satisfaction | 1 hour | Measured by questionnaire ( scale from 1 to 5 ) |
| Gastroenterologist satisfaction | 1 hour | Measured by questionnaire ( scale from 1 to 5 ) |
Countries
Saudi Arabia
Outcome results
None listed