Frailty Syndrome
Conditions
Brief summary
Frailty is common in gastric cancer survivors and seriously affects their prognosis. Multiple longitudinal follow-up assessment of frailty could provide a better understanding of the frailty change of individuals. Our aims were to identify the longitudinal trajectories of frailty and estimate their association with health outcomes in elderly gastric cancer survivors.
Detailed description
Our study suggested the significant heterogeneity in frailty trajectories among elderly gastric cancer survivors, and that different trajectories had different effects on health outcomes. Our results infer the necessity for prevention strategies in elderly gastric cancer survivors to manage heterogeneous frailty trajectories.
Interventions
OTHERobservation
observation
Sponsors
Nanjing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Inclusion criteria
* diagnosed with gastric cancer by endoscopy or pathology; * received radical gastrectomy the first time; * aged ≥60 years; * been able to communicate simply in writing and verbal; * completed the data collection of all follow-up points.
Exclusion criteria
* received radiotherapy or chemotherapy before surgery; * had other sites of malignant tumors; * complicated with severe heart, liver, lung and renal insufficiency; * had physical disability.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| quality of life (QOL) | at 1-year after surgery | used EORTC QLQ-STO22 to assess. |
| disability | at 1-year after surgery | used Elderly Disability Assessment Scale to assess. |
| 1-year hospital readmissions | at 1-year after surgery | captured from medical records. |
| total costs | at 1-year after surgery | captured from medical records. |
Countries
China
Outcome results
None listed