FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05793021

Enrollment

Registered

2023-03-31

Start date

2021-07-08

Completion date

2025-12-31

Last updated

2023-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma

Brief summary

The aim of this interventional study is to investigate the correlation between Magnetic Resonance Phenotype and levels of FKBP51s protein pre and post surgery in adult patients affected by Glioblastoma

Interventions

DIAGNOSTIC_TESTBlood sample

Blood sample pre and post surgery to determine the level of FKBP51s protein

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \>= 18 years * Diagnosis of Glioblastoma with surgery criteria * Brain MRI with contrast both pre and post surgery

Exclusion criteria

* No availability of radiological documentation * Glioblastoma diagnosis not confirmed by Histological examination * Withdrawal of ICF

Design outcomes

Primary

Measure	Time frame
Correlation between FKBP51s protein concentration in Blood Cells and Disease flow	1 week

Secondary

Measure	Time frame
Correlation between FKBP51s protein concentration in Blood Cells and PDL1 expression, Brain MRI phenotype and survival	1 year

Countries

Italy

Contacts

Primary ContactSimona Gaudino, MD

simona.gaudino@policlinicogemelli.it0630155464

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026