Healthy
Conditions
Brief summary
The aims of the study were to evaluate safety of sticker pads containing lavender and ylang ylang oil in healthy volunteers.
Detailed description
The lavender and ylang ylang oil pad was attached to the shirts of healthy volunteers for 2 hours. The outcomes were evaluated before, during and 30 minutes after removal of the pad. Adverse reactions, irritation score, and quality of life were assessed. Blood pressure and pulse rate were also measured
Interventions
Sticker pads , size 160 mm2, were produced by a certified ISO 9001 manufacturer and contained 0.3% lavender oil and 0.7% ylang ylang oil. The sticker pad was attached to the shirts of healthy volunteers for 2 hours. The outcomes were evaluated before, during and 30 minutes after removal of the pad.
Sponsors
Chulalongkorn University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18 to 60 years * no allergic history of lavender and ylang ylang oil * no dermatological diseases, immunocompromised diseases, seizures, asthma, or respiratory diseases.
Exclusion criteria
* an unstable condition of other diseases * olfactory problems * pregnancy * lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adverse reactions of the respiratory tract, skin, eye, and central nervous system | 2 hours | The severity scores were 0 (no symptoms) to 3 (severe symptoms) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Irritation of eye, respiratory, other neurological, and toxicity reaction | 2 hours | Using a 0 to 100 scale, following an increase of severity |
| Systolic blood pressure | 2 hours | Measure systemic blood pressure in mmHg |
| Diastolic blood pressure | 2 hours | Measure diastolic blood pressure in mmHg |
| Pulse rate | 2 hours | Measure pulse rate in beats/minutes |
| Rhinoconjunctivitis quality of life questionnaire | 2 hours | Using a score of 1 (no problems) to 5 (severe problem) |
Countries
Thailand
Outcome results
None listed