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Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05791123
Enrollment
14
Registered
2023-03-30
Start date
2018-07-15
Completion date
2023-03-05
Last updated
2023-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Regeneration

Brief summary

fourteen patients requiring extraction of one posterior tooth with lost buccal bone (\>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

Interventions

PROCEDUREa bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Sponsors

Future University in Egypt
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Patients required implant treatment after tooth extraction * Age group ranged from 20-60 years old. * Patients could undergo the treatment under local anesthesia. * Loss of buccal bone (\>50%) confirmed by preoperative cone beam computed tomography (CBCT). * Presence of other socket walls; mesial, distal and lingual walls. * Tooth needed to be extracted in upper or lower posterior regions

Exclusion criteria

* Uncontrolled diabetic diseases. * Uncontrolled hypertension, or hepatic and renal disorders. * Any systemic diseases associated with bone metabolism.

Design outcomes

Primary

MeasureTime frameDescription
the change in alveolar bone width and height in mm using CBCT scans.6 monthsCone Beam Computed Tomography were taken for each patients before tooth extraction and after 6 months, which were used to assess alveolar ridge changes in width and length in mm.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026