Silodosin, Tamsulosin, Medical Expulsive Therapy, Distal Ureteric Calculi
Conditions
Brief summary
to compare efficacy and safety of Silodosin and Tamsulosin in Medical expulsive therapy of Distal Ureteric Calculi.
Detailed description
to compare efficacy and safety of Silodosin and Tamsulosin in Medical expulsive therapy of Distal Ureteric Calculi in our local setup to find out the optimal drug which promptly and quickly cures the disease thus enabling the person to return to routine activity with less adverse effects.
Interventions
DRUGSilodosin
The patients used Silodosin for Medical expulsive therapy of ureteric calculi
DRUGTamsulosin
The patients used Tamsulosin for Medical expulsive therapy of ureteric calculi
Sponsors
Armed Forces Institute of Urology, Rawalpindi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* symptomatic, unilateral, single, uncomplicated Distal Ureteric Calculi of \<10 mm in size (on plain CT KUB)
Exclusion criteria
* solitary kidney, bilateral ureteric stones, UTI, renal impairment, high-grade hydronephrosis (Grades 3 and 4), any history of previous endoscopic or surgical interventions, pregnancy, diabetes mellitus,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stone clearance rate | upto 4 weeks | Stone clearance rate |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stone expulsion time | upto 4 weeks | Stone expulsion time |
Countries
Pakistan
Outcome results
None listed