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Cardiopulmonary Rehabilitation for Post-acute COVID-19 Symptoms

Hospital- Versus Home-based Cardiopulmonary Rehabilitation for Post-acute COVID-19 Symptoms

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05787353
Enrollment
88
Registered
2023-03-28
Start date
2021-04-16
Completion date
2021-07-31
Last updated
2023-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary

Brief summary

The purpose of this RETROSPECTIVE study was to compare the effect of a hospital and home-based cardiopulmonary rehabilitation (CPR) program on exercise endurance and quality of life in post-acute COVID-19 patients. 88 post-acute COVID-19 patients were divided two groups according to receiving hospital (n=45) or home-based CPR (n=43)in our rehabilitation clinic between January and July 2021. Both protocols consisted of aerobic, breathing and flexibility exercises. Hospital-based CPR: three or four days per week for a total of 20 sessions. Home-based CPR: three or four days/a week over a period of six weeks. The results of six meters walk test (6MWT) for exercise endurance as a main outcome measure, and Borg-dyspnea/fatigue, the visual analog scale (VAS) for pain and the Short Form-36 (SF-36) as secondary outcome measures before and after treatment were recorded.

Interventions

OTHERExercise programme

Both protocols consisted of aerobic, breathing and flexibility exercises. Hospital-based CPR: three or four days per week for a total of 20 sessions. Home-based CPR: three or four days/a week over a period of six weeks.

Sponsors

Eskisehir City Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* being 18 years or older * having COVID-19 treatment (home quarantine/hospital/intensive care unit) according to a positive polymerase chain reaction (PCR) test in a nasopharyngeal + oropharyngeal swab or chest computed tomography (CT) * participating in a home-based exercise program (for 6 weeks) or hospital-based CPR (for 12-20 sessions) due to post-acute COVID-19 symptoms (fatigue, myalgia, dyspnea).

Exclusion criteria

* Patients who had both a negative PCR test and chest CT * Patients who had not completed the six minute walk test (6MWT), Borg scales, Short Form-36 and Visual analog scale-pain. * Acute COVID-19 patients (patients whose symptoms had started less than one month previous)

Design outcomes

Primary

MeasureTime frameDescription
Exercise enduranceOne day before exercise programme start and one day later exercise programme endsSix minutes walk test (All patients walked along a 30-meter-long corridor without obstacles at their normal walking speed, how many meters they walked was noted.)

Secondary

MeasureTime frameDescription
DyspneaOne day before exercise programme start and one day later exercise programme endsBorg scale were also measured before and after 6MWT for perceived dyspnea (scale range from 0 to 10)
Muscle fatigueOne day before exercise programme start and one day later exercise programme endsBorg muscle fatigue (scale range from 6 to 20: higher values show more severe symptoms)
short form 36One day before exercise programme start and one day later exercise programme endsA quality-of-life assessment was performed using the Short Form-36, which has 36 items regarding physical function, physical role, emotional role, energy, body pain, mental health, general health, and social function. The scale ranges from 0 (poor health) to 100 (perfect health)
Musculoskeletal PainOne day before exercise programme start and one day later exercise programme endsVisual analog scale-pain was used to measure general body musculoskeletal pain, which was assessed from 0 (no pain) to 10 (worst possible pain)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026