Helicobacter Pylori-positive With Functional Dyspepsia
Conditions
Brief summary
In patients with Helicobacter pylori-positive functional dyspepsia, long-term follow-up for 6 months after standard triple therapy first-line eradication treatment, the rate of symptom disappearance and degree of improvement of functional dyspepsia were confirmed through changes in symptom scores and changes in drug usage, and eradication treatment The purpose of this study is to confirm the rate of symptom disappearance according to the results.
Interventions
DRUGK-CAB
Tegoprazan 50 mg 1 tab twice daily Amoxicillin 500mg 2 cap twice daily Clarithromycin 500mg 1tab twice daily
Sponsors
Wonkwang University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Male and female outpatients between the ages of 19 and 75 * Who have symptoms of functional dyspepsia (early fullness, postprandial discomfort, epigastric pain, epigastric soreness) that correspond to Rome criteria 4 (diagnostic criteria questionnaire)
Exclusion criteria
* Small intestine and large intestine disease within 6 months of the screening visit (Visit 1) * liver, pancreatobiliary disease within 6 months of the screening visit (Visit 1) * peptic ulcer within 6 months of the screening visit (Visit 1)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of disappearance of dyspepsia symptoms | Day 176 | Rate of disappearance of dyspepsia symptoms after 6 months of eradication treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Improvement rate of dyspepsia symptoms | Day 92, Day 176 | Change rate of dyspepsia symptoms after 3 months and 6 months of eradication treatment |
| Number of days of dyspepsia drug administration | Day 92, Day 176 | Number of days of dyspepsia drug administration after 3 months and 6 months of eradication treatment compared to baseline |
Countries
South Korea
Contacts
Primary ContactNam Suk Lee
Backup ContactJong Min Lee
Outcome results
None listed