Fracture Infection, Open Fracture, Trauma, Trauma Injury
Conditions
Brief summary
This is a pilot prospective, observational study of patients with open or infected fracture evaluating the feasibility and acceptability of OCT, a light-based imaging modality that requires no drug or contrast agent.
Interventions
PROCEDUREOpen Fracture
Patients 18 years of age or older with open fracture. Provision of informed consent.
PROCEDUREInfected Fracture
Patients 18 years of age or older with infected fracture. Provision of informed consent.
Sponsors
Dartmouth-Hitchcock Medical Center
Dartmouth College
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18 years or older * Open fracture * Fracture Related Infection
Exclusion criteria
* Metatarsal fractures
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility and acceptability of OCT imaging | 36 months | The primary objective of this work is to demonstrate feasibility, acceptability, and preliminary effectiveness of Optical Coherence Tomography (OCT) to image bacteria and biofilm. Data will be analyzed accordingly: The association between optical imaging parameters (particularly around biofilm and bacterial contamination) and (1) surgical wound severity and (2) development of infection or treatment failure for infection. |
Countries
United States
Contacts
CONTACTHolly B Symonds
CONTACTDevin S Mullin
PRINCIPAL_INVESTIGATORIda L Gitajn
Dartmouth-Hitchcock Medical Center
Outcome results
None listed