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Health Opportunities and Promoters of Equitable Screening for Lung Cancer

Health Opportunities and Promoters of Equitable Screening for Lung Cancer (HOPES for Lung Cancer)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05784922
Acronym
HOPES
Enrollment
2000
Registered
2023-03-27
Start date
2023-02-03
Completion date
2028-01-31
Last updated
2025-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diagnosis, Lung Cancer, Smoking Behaviors

Keywords

lung cancer screening, Hispanic outreach, educational intervention, digital health, smoking documentation, smoking history, health equity

Brief summary

The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: * What barriers do current and former Hispanic smokers face in the identification and documentation of their smoking status? * How can digital delivery of an educational video promote LCS uptake among current and former Hispanic smokers? Participants will receive an educational video about lung cancer screening and complete brief, self-reported surveys afterwards.

Detailed description

Lung cancer remains the leading cause of cancer-specific mortality in the US, and Hispanics experience worse lung cancer outcomes and die at higher rates due to advanced stage at presentation. Lung cancer screening (LCS) can save many lives through early lung cancer detection among Hispanic current and former smokers. Still, without increasing efforts to improve smoking status disclosure and documentation and tailored interventions to promote LCS uptake among Hispanic current and former smokers, this underserved population will continue to demonstrate disparities in lung cancer survival. Based on prior research experience, Dr. Flores has adapted the NIMHD research framework by incorporating elements from Ford's evidence-based theoretical model to guide the following proposed study aims: 1\) To elucidate barriers and facilitators to consistent identification and documentation of smoking status to promote LCS uptake among Hispanic current and former smokers; 2) To assess feasibility, acceptability, and reach of the digital delivery of an educational video to promote LCS uptake among Hispanic current and former smokers; 3) To explore the effect of the digital delivery of the educational video to increase interest, intent, and scheduling of LCS uptake among Hispanic current and former smokers. Impact: The successful completion of this research will serve as a foundation for developing novel interventions to overcome disparities and advance equity in lung cancer outcomes among Hispanics and other vulnerable populations.

Interventions

OTHEREducational Lung Cancer Screening (LCS) Video

An educational video on lung cancer screening tailored to Hispanic current and former smokers.

Sponsors

National Cancer Institute (NCI)
CollaboratorNIH
Massachusetts General Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
50 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Must be 50-80 years old * Are a current or former smoker (quit within 15 years, or a cumulative smoking status of \> 20 pack-years) * Not currently enrolled in Lung Cancer Screening * Must speak English or Spanish

Exclusion criteria

* Has a clinical cognitive inability to provide informed consent for participation in the study or complete a brief survey * Currently diagnosed with lung cancer * Currently enrolled in lung cancer screening * Have participated in the focus groups discussions from Aim 1

Design outcomes

Primary

MeasureTime frameDescription
Participant outreach (contact) of digital linkYear 3Reach is defined as \>20% of enrolled participants interacting with the digital delivery of the LCS educational video (i.e., partial or complete review of the LCS educational video).

Secondary

MeasureTime frameDescription
Participant interaction with digital linkYear 3Overall proportion of participants that click on the embedded link to the successfully digitally delivered LCS educational videos
Participant attention of LCS videoYear 3Duration of viewing the LCS video (i.e., partial or complete)
Survey completionYear 4Overall proportion of survey completion by participants.

Other

MeasureTime frameDescription
Participant baseline smoking statusYear 5Identify salient participant characteristics obtained from the EHR (e.g., smoking status) among those that interacted with the digital delivery modality.
Participant acceptability of interventionYear 5Investigate attributes of the intervention to guide future research and development to create such an intervention (for future trials)

Countries

United States

Contacts

Primary ContactEfren Flores, MD
ejflores@mgh.harvard.edu617-724-4254

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026