Cardiopulmonary Arrest, Out-Of-Hospital Cardiac Arrest
Conditions
Keywords
Intoxication, Prehospital POCUS, CPR, Sonography, Blood gas analysis, Cardiac arrest, OHCA, Reversible causes, Tele-support, Checklist, Prehospital emergency physician, Emergency medicine
Brief summary
Management of the reversible causes in cardiac arrest is fundamental for successful treatment of out-of-hospital cardiac arrests. Point-of-care diagnostics as prehospital emergency ultrasound, blood gas analysis and toxicological screening support the diagnostic process of evaluating potential reversible causes. Digital tools provide support of a structured approach. This study aims to evaluate the frequency of reversible causes during OHCA as well as specific interventions due to these findings. Furthermore, CPR performance (hands-off, ROSC, 30-day mortality) and cognitive load of the prehospital emergency physician will be investigated. In total 100 patients with OHCA will be included in this study. Identification of reversible causes will be performed upon a structured protocol using an interactive checklist. Cognitive load of emergency physician as well as CPR parameter (frequency of reversible causes, hands-off, ROSC, 30-day mortality) will be analysed.
Interventions
DIAGNOSTIC_TESTChecklist for evaluation of reversible causes
Prehospital evaluation by checklist and diagnostic testing for reversible causes of OHCA using point-of-care blood gas analysis, saliva toxicological screen and ultrasound and post-hoc toxicological analysis of blood using mass spectrometry
Sponsors
Medical University of Vienna
Seibersdorf Labor GmbH
Ludwig Boltzmann Institute for Digital Health and Prevention
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with prehospital cardiac arrest, where POCUS, blood gas analysis as well as screening for intoxication can integrated in ALS rhythm without delay of life-saving treatment or transportation will be included.
Exclusion criteria
* Patients will be excluded under the age of 18, or if POCUS, blood gas analysis will lead to a delay of live-saving treatment or transportation. Furthermore, pregnant patients will be excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of reversible causes in OHCA and alterations of treatment | up to 30 days | The primary outcome of this study evaluates the frequency of reversible causes during OHCA. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of ROSC | up to 30 days | Any prehospital ROSC/sustained ROSC/in-hospital ROSC |
| 30-day mortality | up to 30 days | rate of mortality within 30 days in case of hospital admission |
| Hands-off time | During study completion, up to 120 min | Hands-off time during process of identification of reversible causes |
| Cognitive load | 1 year (evaluation in documentation phase after CPR) | NASA Task Load Index evaluated by the prehospital emergency physician after rescue mission |
Countries
Austria
Outcome results
None listed