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An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors

An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05784207
Enrollment
145
Registered
2023-03-24
Start date
2017-06-01
Completion date
2021-12-30
Last updated
2023-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Radiomics

Brief summary

The purpose of this study is to compare AI performance to doctor's performance in the evaluation of IPF/UIP and ILDs without UIP(proven by biopsy).

Interventions

OTHERRadiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

The aim is to evaluate the performance of AI with the performance of doctors

Sponsors

Maastricht University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

\- the availability of non-contrast-enhanced HRCT

Exclusion criteria

* the use of contrast enhancement * images containing metal or motion artifacts * Images reconstructed with a slice thickness larger than 1.5 mm

Design outcomes

Primary

MeasureTime frameDescription
The performance of Radiomics algorithm compared to the ground truthMay 2021Reporting the performance measure: accuracy

Secondary

MeasureTime frameDescription
Comparing the performance of the radiomics algorithm to that of physiciansJune 2021Correctness of the diagnosis - the most probable thin-section pattern (dichotomous outcome: yes or no)

Other

MeasureTime frameDescription
Comparing the performance of radiomics algorithm to that of individual doctorJune 2021Correctness of the diagnosis - the most probable thin-section pattern (dichotomous outcome: yes or no)
Comparing the reproducibility of diagnosis between the doctorsJune 2021Measuring the concordance in diagnosis in between the physicians, and for each physician separately, using the Concordance correlation coefficient.

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026