Atrial Fibrillation, Osa Syndrome
Conditions
Brief summary
This study aims to identify how many patients who have atrial fibrillation, also have sleep apnoea. This is important because sleep apnoea can be a trigger to atrial fibrillation and it can be corrected with a simple intervention. Therefore it is important to understand its prevalence (how many patients with atrial fibrillation are affected by it). Also, obesity and sleep disorders are often associated, therefore the evolution of atrial fibrillation is studied in patients who also have obesity and have lost weight compared with patients who did not loose any weight or are not obese. As medications or therapy are not changed, this is an observational study.
Interventions
DIAGNOSTIC_TESTPolysomnography
Study of the sleep pattern
BEHAVIORALLifestyle counselling
Weight loss counselling
Sponsors
Istituto Auxologico Italiano
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Inclusion criteria
primary outcome: * 1 episode of atrial fibrillation in the previous year Inclusion Criteria secondary outcome: * BMI \> o = 27Kg/m2 * AHI \>30 o con 15\<AHI\<30 associated with other symptoms (sleeplessness, uncontrolled hypertension and cerebral events)
Exclusion criteria
* Ejection Fraction \<50% * HFpEF not related to atrial fibrillation. * coronary artery disease * valvular cardiomyopathy * patient already in treatment for sleep apnoea * hyperthyroidism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in prevalence of obstructive sleep apnoea in patients with atrial fibrillation | Baseline and at 3, 6, 12, 24 and 36 months | Change in prevalence of obstructive sleep apnoea from baseline to 3 years |
| Percentage of men and women with obstructive sleep apnoea in patients with atrial fibrillation | Baseline | Percentage of men and women with obstructive sleep apnoea in patients with atrial fibrillation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in body weight | Baseline and at 3, 6, 12, 24 and 36 months | Change in body weight from baseline to 3 years |
| Change in incidence of atrial fibrillation recurrencies | Baseline and at 3, 6, 12, 24 and 36 months | Change in incidence of atrial fibrillation recurrencies from baseline to 3 years |
| Change in quality of life | Baseline and at 3, 6, 12, 24 and 36 months | Change in quality of life from baseline to 3 years |
Countries
Italy
Outcome results
None listed