GINGIVAL RECESSION
Conditions
Keywords
Gingival recession, free subepithelial connective tissue graft, collagen membrane, growth factor enhanced matrix 21 s
Brief summary
The study aimed to compare, the effectiveness of Growth Factor Enhanced Matrix (GEM 21s) ® combined either with free connective tissue graft or collagen membrane in the treatment of Miller class II gingival recession.
Detailed description
Materials and Methods: Twenty sites in 10 patients, with class II Miller gingival recession were allocated randomly to be treated by (GEM 21s) ® with free connective tissue graft (groupI) or GEM 21s with collagen membrane (groupII). Plaque index, bleeding on probing, recession width, recession depth, height of keratinized tissue and digital measurements were recorded at baseline, 1, 3 and 6-months'. Probing pocket depth, clinical attachment level, gingival thickness and Radiographic parameters were recorded at baseline and 6 months'. Root coverage percentage were recorded 6 months postoperative and wound healing index were recorded at 1,3 and 6-months' post-operative .
Interventions
PROCEDUREGROUPI
10 sites treated with Free connective tissue graft (FCTG) + growth factors enhanced matrix 21 s GEM 21S + coronally advanced flap (CAF)
PROCEDUREGROUP II
10 sites treated withCollagen membrane + GEM 21S + coronally advanced flap (CAF)
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
25 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* lack of any related medical issues that contraindicate periodontal surgery, * optimum adherence as confirmed by a positive attitude towards oral hygiene, and successfully showing up for treatment appointments. * No history of any medications in the previous six months that may interfere with periodontal surgery Gingival thickness for the selected sites should be \> 1mm (as measured 2mm apical to gingival margin), * Clinical attachment level ≥ 4mm measured from cemento-enamel junction till the deepest probing depth.
Exclusion criteria
* the presence of class V caries or restoration in the site to be treated, * previous mucogingival surgery at the selected site. * Teeth that are tilted, rotated, or have any occlusal abnormalities. * Smokers and pregnant patients were excluded from the participation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of root coverage | up to 6 months | according to the following formula: (RD at baseline - RD at 6 months) / RD at baseline)x100 was calculated after 6 months |
| recession depth | up to 6 months | The distance between the CEJ and the gingival margin at the midbuccal aspect of the involved tooth measured at baseline , 1, 3, and 6 months |
| Height of keratinized tissue | up to 6 months | distance from the most apical point of the free gingival margin to the mucogingival junction mid-facially measured at baseline , 1, 3, and 6 months |
| Gingival thickness (Gingival biotype) | up to 6 months | measured at mid-buccal area 2 mm apical to the free gingival margin measured at baseline, and 6 months postoperatively |
| radiographic measurements of facial bone level, thickness and density | up to 6 months | from cone beam CT radiography measured at baseline, and 6 months postoperative |
| Recession width | up to 6 months | the distance between the mesial and distal papillae along the CEJ measured at baseline , 1, 3, and 6 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| clinical attachment level | up to 6 months | measured from CEJ to the bottom of the pocket measured at baseline, 3, and 6 months |
| Digital measurements | up to 6 months | all recession areas were photographed The photos were taken by a digital camera at a fixed resolution (mega pixel) taken at baseline, 1,3,and 6 months postoperative |
| healing index | up to 6 months | recorded at 1, 3 and 6 months postoperatively (Score 1: uneventful healing while score 3: poor wound healing |
| probing pocket depth | up to 6 months | measured from gingival margin to the bottom of the pocket measured at baseline, 3, and 6 months |
Countries
Egypt
Outcome results
None listed