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Effect of Prolonged Slow Expiration Technique on Blood Gases Among Pneumatic Neonates

Effect of Prolonged Slow Expiration Technique on Blood Gases Among Neonates With Pneumonia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05781464
Enrollment
32
Registered
2023-03-23
Start date
2023-04-01
Completion date
2023-11-17
Last updated
2023-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Brief summary

Pneumonia is a medical condition that, if not treated promptly, can lead to life- threatening complications. The prolonged slow expiration technique is a new type of chest physiotherapy that helps infants discharge bronchial secretions which accumulated due to pneumonia.

Detailed description

Pneumonia is an infective lung condition that is one of the most common risk factors for neonatal death. Pulmonary infections, most common caused by anaerobic bacterial infection, result in the accumulation of pus in the pleural cavity. Preterms, neonates with respiratory infections, and underdeveloped lungs all require the use of a prolonged slow expiration technique. Prolonged slow expiration technique is the only chest clearance technique that provides both effective clearance and a soothing effect. Another recommendation for this technique is lack of application of emerging techniques of respiratory physiotherapy. Although the technique is effective, it is rarely in practice over the conventional methods of chest physiotherapy. During prolonged slow expiration, intrathoracic pressure gradually rises due to thoracoabdominal compression, preventing bronchial collapse and flow disruption that occurs during forced expirations.

Interventions

Postural drainage: the patient is positioned in postural drainage so that gravity had the maximum effect on the lung segment that needed to be drained, all lung zones are emphasised in positional initiatives for babies. Percussion is the rhythmic striking of the chest wall with cupped hands for 1 to 2 minutes at a time. Vibration is performed by placing fingers on the chest wall over the segment being drained and isometrically contracting the forearm and hand muscles to produce a vibratory motion. Vibration is accomplished either through manual vibratory motion of the therapist's fingers on the infant's chest wall or through the use of a mechanical vibrator ( Foreo vibrator).

PROCEDUREProlonged slow expiration technique

The therapist places one hand on the thorax below the suprasternal notch and the other hand over the upper abdomen while the neonate is supine. Both hands will have hypothenar contact with the thorax and abdomen. At the end of the expiratory phase, the therapist places a compression force with both hands. Compression at the end of expiration with hypothenar eminence is kept for 2 or 3 breathing cycles. This technique is repeated several times, with a rest time between applications of about 5 or 10 spontaneous breaths.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
1 Days to 2 Months
Healthy volunteers
No

Inclusion criteria

* Age since birth till 2 months * Clinical findings of pneumonia: tachypnea, chest recession, fever, cyanosis and cough * Radiological diagnosis of pneumonia (x-ray): lober or segmental consolidation, nodular or coarse patchy infiltration, diffuse haziness and air bronchogram. * Neonates on oxygen therapy.

Exclusion criteria

* Neonates with congenital cardiopathy. * Neonates with surgical incision in thorax or abdomen. * Neonates with neurological intervention. * Neonates with obstruction of upper air way. * Neonates with gastroesophageal reflux and laryngeal affection.

Design outcomes

Primary

MeasureTime frameDescription
Change in arterial oxygen saturation (Sao2)Change from Baseline SaO2 at 9 daysArterial oxygen saturation is assessed by standardized international monitor and measured by %
Change in systolic and diastolic blood pressureChange from baseline systolic and diastolic blood pressure at 9 daysSystolic and diastolic blood pressure are assessed by standardized international monitor and measured by millimeters of mercury ( mmHg)
Change in heart rate (HR)Change from baseline HR at 9 daysHeart rate is assessed by standardized international monitor and measured by beats per minute (BPM)
Change in temperatureChange from baseline temperature at 9 daysTemperature is assessed by thermometer and measured by degree(°)
Change in power of hydrogen (PH)Change from baseline PH at 9 daysPH is assessed by blood gases machine and it is a scale used to specify the acidity or basicity of blood
Change in partial pressure of carbon dioxide (PaCO2)Change from baseline PaCO2 at 9 daysPaCO2 is assessed by blood gases machine and measured by mmHg and it serves as a marker of sufficient alveolar ventilation within the lungs
Change in bicarbonate (HCO3)Change from baseline HCO3 at 9 daysHCO3 is assessed by blood gases machine and measured by milliequivalents per litre (mEq/L) and it is used to detect electrolyte imbalance

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026