Multi-Cancer Early Detection (MCED) of Firefighters

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05780957

Enrollment

2000

Registered

2023-03-23

Start date

2023-03-21

Completion date

2030-12-31

Last updated

2025-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Keywords

Cancer, Multi-Cancer Early Detection, MCED

Brief summary

This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.

Interventions

OTHERMCED

multi-cancer early detection (MCED) test

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* 18 years of age or older * Currently employed as a firefighter, full-time or part-time * Taking part in Vincere's First Responder Cancer Screening Program * Able to donate blood and urine sample * Able to provide informed consent to participate in the study

Exclusion criteria

* Deemed medically unfit for sample donation * Personal history of cancer in the last 5 years (with the exception of non-melanoma skin cancer)

Design outcomes

Primary

Measure	Time frame
Sensitivity, specificity, positive and negative predictive performance values (PPV and NPV) to detect cancer using Elypta's MCED test, as measured in plasma, in urine, and in plasma and urine combined	Up to 7 years
Sensitivity, specificity, positive and negative predictive performance values to detect cancer using Proteotype's MCED test, as measured in plasma.	Up to 2030

Countries

United States

Contacts

Primary ContactChristine Lau, MD

drlau@vincerecancer.com480-306-5390

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026