COVID-19 Acute Respiratory Distress Syndrome, Death, Extracorporeal Membrane Oxygenation Complication, Quality of Life
Conditions
Keywords
ECMO, COVID-19, quality of life
Brief summary
This study aims to investigate the quality of life and the outcome after veno-venous extracoporeal membrane oxygenation (ECMO) support fir severe acute respiratory syndrome (ARDS) in COVID-19 patients.
Detailed description
The investigators follow our COVID-19 patients supported by ECMO, we make phone calls or real-life visits to pthe patients to score the quality of life, by using the SF-36. The SF-36 measures eight scales: physical functioning, role physical, bodily pain, general health, vitality , social functioning , role emotional , and mental health. The participants are contacted 3 months, 6months, 1year and 2 years after the ECMO support started for evaluation of the SF-36.
Interventions
DEVICEVV-ECMO
veno-venous extracorporeal membrane oxygenation
Sponsors
University Hospital, Ghent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with PCR-confirmed COVID-19 infection AND * Acute Respiratory Distress Syndrome who require veno-venous ECMO therapy.
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| in-hospital mortality | mortality during hospitalisation, up to two years | — |
| Quality of life 1y after ECMO insertion | 1 year | Result of SF-36 1 year after VV-ECMO insertion |
| Quality of life 2y after ECMO insertion | 2 years | Result of SF-36 2 years after VV-ECMO insertion |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lung complications requiring surgical treatment | From the start of VV-ECMO support until weaning of VV-ECMO, up to two years | Hemothorax or lung abcedation |
| LOS hospital | from the day of hospital admission until the day that the participant is transferred to home, up to two years | length of stay at the hospital |
| LOS ICU | from the day of intensive care unit admission until the day of transfer to the ward, up to two years | length of stay at the intensive care unit |
| Duration of mechanical ventilation | 2 years | — |
| death after hospital discharge | after discharge from the hospital upon 2 years after | all-cause death |
| Incidence of acute kidney injury | from the day of hospital admission until the day that the participant is transferred to home, up to two years | — |
Countries
Belgium
Outcome results
None listed