Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization

Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization: A Comprehensive Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05779332

Enrollment

655

Registered

2023-03-22

Start date

2020-02-01

Completion date

2020-06-15

Last updated

2023-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL, Dental Caries, Dental Plaque, Dental Diseases

Keywords

Molar Incisor Hypomineralization, oral health, MIH, Oral health related lif quality, Child Perceptions Questionnaire, OHRQoL, CPQ

Brief summary

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).

Detailed description

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL). The aim of this study was to determine the prevalence, etiology and impacts of MIH on oral health status and OHRQoL. Six hundred and fifty-five parents and their children aged 9 years were included in the study. After parents completed the questionnaire about the etiology of MIH, children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Children were evaluated for presence and severity of MIH, dental caries experience and oral hygiene status. Qualitative data were analyzed with the Pearson chi-square and Fisher's exact tests. For the quantitative data, if the normal distribution was not satisfied, Kruskal Wallis/Mann-Whitney U tests were used. Also, Binominal logistic regression analysis was performed and p\<0.05 was statistical significant. .

Interventions

OTHERsurvey application

Children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Oral examination of children were conducted for presence and severity of MIH, dental caries experience and oral hygiene status.

Study design

Observational model

CASE_CROSSOVER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

9 Years to 9 Years

Healthy volunteers

Yes

Inclusion criteria

* Being 9-year-old, * Mentally and physically capable of completing the questionnaire, * Presence of fully erupted 4 permanent molars and 8 permanent incisors.

Exclusion criteria

* Children were receiving orthodontic treatment during the examination, * Children had enamel hypoplasia or developmental defects, * Children had amelogenesis imperfecta or dental fluorosis.

Design outcomes

Primary

Measure	Time frame	Description
To determine the prevalence and etiology of MIH.	up to four months	A questionnaire was applied to the parents about the etiological factors and the prevalence of MIH was determined by oral examination.
To evaluate the impacts of MIH on oral health status.	up to six months	Oral health was evaluated by recording dmft (decayed, missing and filled teeth) and plaque index values.
To evaluate the impacts of MIH on OHRQoL.	up to six months	The impact of MIH on quality of life (OHRQoL) was measured with the Child Perception Questionnaire (CPQ8-10).

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026