Adaptive Behavior, Perception of Things Changing Color
Conditions
Keywords
Visual Perception, Visual Adaptation, Color Perception
Brief summary
Participants will be given experience wearing colored lenses that add a tint to the environment. Changes in visual perception and neural processing that arise as a result of this experience will be measured. These are expected as participants learn to switch to colored lenses mode where the effects of the lenses are discounted and colors appear more normal as soon as the lenses are put on.
Detailed description
All participants will wear tinted lenses for 1 hour at a time, 5 times per day. Perception (behavior) and neural function (with functional MRI and EEG) before and after this experience will be measured. In the neural measurements, activity will be recorded while participants view stripes of many different colors both with the lenses on and off. In the perceptual measurements, participants will adjust the color of a small patch to appear neutral, neither red nor green. Behavior will be measured in a variety of conditions to test different hypotheses about the origins of the mode-switching effects. These include: 1) surrounding the patch with different colors, 2) preceding the presentation of the patch with presentation of different colors, 3) presenting the tests in a red-illuminated room, 4) presenting the tests in a completely darkened room, and 5) using a head-mount-display (virtual reality goggles) to present simulated lenses that gradually change in strength.
Interventions
BEHAVIORALMode Switching Training
Wear of colored lenses for 1 hr, 5 times per day, for 5 days
Sponsors
University of Minnesota
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
The interventional study type is correct. The investigative team is giving all subjects a treatment- behavioral training in visual mode switching- and measuring effects of that treatment, by comparing measures made before to measures made after the treatment. Thus, this is a within-subjects, repeated measures experimental design. The experimenters have 6 different measurements they are using this design in different groups of subjects run in parallel, all examining different effects of the same treatment. . This is why parallel study model is appropriate. These parallel groups with different measurements, but same treatment, are the arms of the study.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Normal or corrected to normal vision by contact lenses * No known visual disorders * Little to no experience in tinted environments (e.g. dark rooms, swimming goggles)
Exclusion criteria
* Abnormal color vision
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in unique yellow settings | Change will be assessed over the entire study, by comparing a pre-test the day before the intevention (which lasts 5 days) to a post-test the day after the intervention. | This is a standard psychophysical measure referenced in 100s of papers. Participants adjust a patch of color until it appears neither red nor green and this color is reported in standard colorimetric coordinates (e.g. CIE). |
| Change in BOLD functional MRI activity | Change will be assessed over the entire study, by comparing a pre-test the day before the intevention (which lasts 5 days) to a post-test the day after the intervention. | Neural activation will be measured with functional MRI which will be used to measure BOLD activity with standard methods, and reported as percent change from rest, a standard measure, for each voxel in the brain. |
| Change in EEG activity | Change will be assessed over the entire study, by comparing a pre-test the day before the intevention (which lasts 5 days) to a post-test the day after the intervention. | Neural activity will be measured with electroencephelography using standard techniques and will be reported as voltage changes over time for each electrode in a standard configuration. |
Countries
United States
Outcome results
None listed