Epilepsy
Conditions
Keywords
Epilepsy, Stereoelectroencephalography, Speech
Brief summary
Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.
Interventions
BEHAVIORALSpeech
Patients read specific words and sentences
Using stereoelectroencephalography to record the Intracranial EEG of the patient
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Patients with focal refractory epilepsy also need preoperative evaluation with SEEG
Exclusion criteria
* History of major depression or psychiatric disorders and medication that causes symptoms of psychiatric disorders * Patients with severe cognitive impairment (MMSE score ≤15), unable to complete the language function test
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Phonetic Feature Encoding in Human Superior Temporal Gyrus | through study completion, an average of 1 year | Phonetic Feature Encoding in Human Superior Temporal Gyrus |
Countries
China
Outcome results
None listed