Mechanical Ventilation
Conditions
Keywords
lung dynamics under general anesthesia, prone position, pressure controlled mode, volume controlled mode, vertabral surgery
Brief summary
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery in the prone position.
Detailed description
The VCV (volume controlled ventilation) mode is the mode commonly used in general anesthesia practice. In VCV mode, the parameters under control are tidal volume and respiratory rate. In VCV mode, airway pressure changes depending on resistance and compliance. There is a risk of increased airway pressures in this mode. In PCV-VG (pressure controlled volume guaranteed ventilation) mode, the parameters under control are the peak airway inspiratory pressure and the I/E ratio. It has been shown that peak airway pressures decrease and partial oxygen pressure increase due to decreased inspiratory flow in this ventilation mode. Both ventilation modes are frequently used in patients undergoing general anesthesia. In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics (pulmonary peak-plateau pressure, compliance, driving pressure, SpO2 and end-tidal carbon dioxide) and hemodynamics (mean arterial pressure and heart rate) in patients undergoing vertebral surgery in the prone position. In the study, patients will be randomized and divided into 2 groups after obtaining informed consent forms. If a mode change is required during the surgery, that patient will be excluded from the study.
Interventions
DEVICEThe mechanical ventilation mode
Changing the mechanical ventilation mode
Sponsors
Izmir Ataturk Training and Research Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients who will undergo thoracolumbar vertebral surgery in the prone position * Patients older than 18 years * Patients younger than 70 years of age * ASA 1-2 patients
Exclusion criteria
* Patients with a BMI \>30 kg/m2 * Patients with a history of chronic pulmonary disease * Patients with a history of previous thoracic surgery * Patients with ASA \>3 * Patients who will undergo emergency surgery * Pregnant patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on lung compliance | 3 months | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on lung compliance (ml/cmH20) in patients undergoing vertebral surgery in a prone position |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of the effects of pressure-controlled volume guaranteed ventilation and volume-controlled ventilation on mean arterial pressure | 3 months | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on mean arterial pressure (mmHg) in patients undergoing vertebral surgery in a prone position |
| Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on heart rate | 3 months | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on heart beats per minute (bpm) in patients undergoing vertebral surgery in a prone position |
Countries
Turkey (Türkiye)
Contacts
Primary ContactDerya A Yurtlu, M.D.
Outcome results
None listed