Drug Use, Mental Illness, Substance Abuse
Conditions
Keywords
Harm Reduction, Latinx/Hispanix, Black/African American, Drug Use, Cocaine, Opioids, Methamphetamines
Brief summary
The purpose of this study is to assess whether an integrated harm reduction intervention (IHRI), compared to harm reduction (HR) services as usual, will improve harm reduction service utilization among Black and Latinx people who use drugs (PWUD).
Interventions
BEHAVIORALIntegrated Harm Reduction Intervention (IHRI)
8-week program targeting areas rooted in the 8 principles of harm reduction. Includes weekly education lessons and informed referrals to social service organizations.
Sponsors
NYU Langone Health
National Institute of General Medical Sciences (NIGMS)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* at least 18 years of age * self-identified as misusing opioids +/- other substances (stimulants) in the past 30 days, confirmed by interview using DSM-5 criteria * English or Spanish speaking * able to provide informed consent.
Exclusion criteria
* inability to provide informed consent or participate in the study procedures as proposed in the consent * active suicidal or homicidal ideation or an unstable psychotic disorder (schizophrenia, schizoaffective disorder) or mood disorder (bipolar disorder, severe major depressive disorder) * an unwillingness to be randomized. * are prisoners
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Participants who Attend At least 1 Harm Reduction (HR) Session after Introductory HR Session | Up to Week 8 | Measure of engagement. |
| Percentage of Participants who Attend at least 3 HR Sessions in Total | Up to Week 8 | Measure of engagement. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline in Number of Days of Opioid/Other Stimulant Use | Baseline, Week 8 | Number of days of opioid/other stimulant use will be calculated using the timeline follow back method, which asks participants to estimate how many days over the previous 30 days that they used opioids/other stimulants. |
| Change from Baseline in Overdose Risk Assessment Tool Score | Baseline, Week 8 | 20-item assessment of overdose risk. Each item prompts a "Yes" or "No" response. If the response is "Yes," a score is assigned for that item. If the answer is "No," no score is assigned for that item. The total score is the sum of responses and ranges from 0 to 42; lower scores indicate low risk, higher scores indicate higher risk. A decrease in scores indicates risk of overdose decreased during the observatioN period. |
| Change from Baseline in Brief Quality of Life Scale Score | Baseline, Week 8 | 12-item assessment of quality of life. Each item is ranked on a 5-point Likert scale ranging from 0 (do not agree at all) to 4 (agree completely). The total score is the sum of responses and ranges from 0 to 48; higher scores indicate higher quality of life. An increase in scores indicates quality of life increased during the observation period. |
Countries
United States
Contacts
CONTACTAyana Jordan, MD, PhD
PRINCIPAL_INVESTIGATORAyana Jordan, MD, PhD
NYU Langone Health
Outcome results
None listed