Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children

Evaluation of Giomer Varnish Versus Fluoride Varnish on The Color Improvement of White Spot Lesions in Permanent Teeth of Children: A Randomized Controlled Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05775250

Enrollment

Registered

2023-03-20

Start date

2023-03-15

Completion date

2024-01-30

Last updated

2024-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White Spot Lesion

Keywords

white spot lesion, fluoride varnish, Giomer Varnish

Brief summary

A randomized control trial evaluating the effect of the Giomer varnish versus fluoride varnish on the color improvement of the white spot lesion in permanent anterior teeth of children aged between 8-14 years by using a spectrophotometer at baseline, after 1 month, 3 months and 6 months

Interventions

DRUGgiomer varnish

Giomer varnish containing surface pre-reacted glass-ionomer (PRG) filler, will be administrated once.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

8 Years to 14 Years

Healthy volunteers

Yes

Inclusion criteria

* • Patients with good general health. * Adequate oral hygiene, * Patients who didn't receive remineralizing agents during the last 3 months other than regular toothpaste.

Exclusion criteria

* Uncooperative child. * Active carious lesion. * Labial surface restoration.

Design outcomes

Primary

Measure	Time frame	Description
white spot lesion color change	6 months	assessment of white spot lesion color by using spectrophotometer

Secondary

Measure	Time frame	Description
Patient response to the treatment	6 months	Patient response to the treatment using facial image scale, scores from 1 to 5

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026